Annotations: 2LQ6

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF13832	e2lq6A1	A: few secondary structure elements	X: RING/U-box-like	H: RING/U-box-like	T: FYVE/PHD zinc finger	F: PF13832	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF13832	PHD-zinc-finger like domain (zf-HC5HC2H_2)	PHD-zinc-finger like domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Bromodomain-containing protein 1	protein binding binding histone binding histone reader activity chromatin-protein adaptor activity protein-macromolecule adaptor activity molecular adaptor activity cation binding ion binding metal ion binding small molecule binding	developmental process multicellular organismal process regulation of biological process regulation of multicellular organismal development regulation of cellular process cellular developmental process regulation of developmental process hemopoiesis biological regulation cell development regulation of cell differentiation regulation of cell development multicellular organism development cell differentiation immune system process developmental process multicellular organismal process regulation of biological process regulation of multicellular organismal development regulation of cellular process cellular developmental process regulation of developmental process hemopoiesis biological regulation cell development regulation of cell differentiation regulation of cell development multicellular organism development cell differentiation immune system process anatomical structure development regulation of hemopoiesis cellular process regulation of immune system process regulation of multicellular organismal process response to electrical stimulus response to stimulus response to abiotic stimulus cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process cellular metabolic process primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process homeostatic process positive regulation of biological process positive regulation of developmental process positive regulation of cell differentiation myeloid cell homeostasis positive regulation of cellular process erythrocyte homeostasis regulation of myeloid cell differentiation erythrocyte differentiation regulation of erythrocyte differentiation positive regulation of erythrocyte differentiation multicellular organismal-level homeostasis myeloid cell differentiation positive regulation of myeloid cell differentiation homeostasis of number of cells response to immobilization stress response to stress transcription by RNA polymerase II regulation of transcription by RNA polymerase II erythrocyte development erythrocyte maturation developmental maturation anatomical structure maturation myeloid cell development cell maturation protein-DNA complex organization cellular component organization protein-containing complex organization chromatin organization chromatin remodeling cellular component organization or biogenesis	somatodendritic compartment cell body perikaryon neuronal cell body cellular anatomical entity membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nuclear speck nuclear body intracellular organelle somatodendritic compartment cell body perikaryon neuronal cell body cellular anatomical entity membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nuclear speck nuclear body intracellular organelle nucleoplasm organelle lumen organelle nuclear lumen cell projection dendrite dendritic tree neuron projection plasma membrane bounded cell projection protein-containing complex catalytic complex histone H3-K14 acetyltransferase complex protein-DNA complex nuclear protein-containing complex chromatin chromosome transferase complex H3 histone acetyltransferase complex histone acetyltransferase complex acetyltransferase complex intracellular non-membrane-bounded organelle protein acetyltransferase complex intracellular protein-containing complex non-membrane-bounded organelle MOZ/MORF histone acetyltransferase complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR001965	Zinc finger, PHD-type	Domain
A	IPR018359	Bromodomain, conserved site	Conserved Site
A	IPR001487	Bromodomain	Domain
A	IPR000313	PWWP domain	Domain
A	IPR042009	BRPF2, PHD domain	Domain
A	IPR019787	Zinc finger, PHD-finger	Domain
A	IPR011011	Zinc finger, FYVE/PHD-type	Homologous Superfamily
A	IPR019542	Enhancer of polycomb-like, N-terminal	Domain
A	IPR019786	Zinc finger, PHD-type, conserved site	Conserved Site
A	IPR034732	Extended PHD (ePHD) domain	Domain
A	IPR013083	Zinc finger, RING/FYVE/PHD-type	Homologous Superfamily
A	IPR036427	Bromodomain-like superfamily	Homologous Superfamily
A	IPR042004	BRPF2, ePHD domain	Domain

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: O95696	adenoid cystic carcinoma salivary gland adenoid cystic carcinoma osteosarcoma schizophrenia bipolar disorder ovarian cancer subependymal giant cell astrocytoma medulloblastoma tuberculosis

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.