2LGS

FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C	d2lgsc1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
C	d2lgsc2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
E	d2lgse1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
E	d2lgse2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
H	d2lgsh1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
H	d2lgsh2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
L	d2lgsl1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
L	d2lgsl2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
A	d2lgsa1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
A	d2lgsa2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
B	d2lgsb1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
B	d2lgsb2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
D	d2lgsd1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
D	d2lgsd2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
F	d2lgsf1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
F	d2lgsf2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
G	d2lgsg1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
G	d2lgsg2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
I	d2lgsi1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
I	d2lgsi2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
J	d2lgsj1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
J	d2lgsj2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
K	d2lgsk1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	Glutamine synthetase, N-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)
K	d2lgsk2	Alpha and beta proteins (a+b)	Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	Glutamine synthetase catalytic domain	Glutamine synthetase, C-terminal domain	(Salmonella enterica subsp. enterica serovar Typhimurium ) [TaxId: 90371 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Glutamine synthetase/guanido kinase	8036260	3000676	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GS N-terminal domain-like	8034612	3000408	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	PF03951	e2lgsC2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
C	PF00120	e2lgsC1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
E	PF03951	e2lgsE2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
E	PF00120	e2lgsE1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
H	PF03951	e2lgsH2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
H	PF00120	e2lgsH1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
L	PF03951	e2lgsL2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
L	PF00120	e2lgsL1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
A	PF03951	e2lgsA2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
A	PF00120	e2lgsA1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
B	PF03951	e2lgsB2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
B	PF00120	e2lgsB1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
D	PF03951	e2lgsD2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
D	PF00120	e2lgsD1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
F	PF03951	e2lgsF2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
F	PF00120	e2lgsF1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
G	PF03951	e2lgsG2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
G	PF00120	e2lgsG1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
I	PF03951	e2lgsI2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
I	PF00120	e2lgsI1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
J	PF03951	e2lgsJ2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
J	PF00120	e2lgsJ1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)
K	PF03951	e2lgsK2	A: beta barrels	X: Ribosomal protein L25-like	H: Glutamine synthetase, N-terminal domain (From Topology)	T: Glutamine synthetase, N-terminal domain	F: PF03951	ECOD (1.6)
K	PF00120	e2lgsK1	A: a+b two layers	X: Glutamine synthetase-like	H: Glutamine synthetase/guanido kinase (From Topology)	T: Glutamine synthetase/guanido kinase	F: PF00120	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
C	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
E	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
E	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
H	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
H	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
L	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
L	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
A	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
A	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
B	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
B	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
D	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
D	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
F	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
F	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
G	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
G	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
I	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
I	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
J	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
J	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)
K	3.10.20.70	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Glutamine synthetase, N-terminal domain	CATH (4.3.0)
K	3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase	Chain A, domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF00120	Glutamine synthetase, catalytic domain (Gln-synt_C)	Glutamine synthetase, catalytic domain	-	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF03951	Glutamine synthetase, beta-Grasp domain (Gln-synt_N)	Glutamine synthetase, beta-Grasp domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	GLUTAMINE SYNTHETASE	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding cation binding manganese ion binding transition metal ion binding metal ion binding acid-ammonia (or amide) ligase activity ammonia ligase activity glutamine synthetase activity catalytic activity ligase activity, forming carbon-nitrogen bonds ligase activity	response to nutrient levels cellular homeostasis chemical homeostasis response to stimulus homeostatic process intracellular nitrogen homeostasis nitrogen utilization intracellular chemical homeostasis cellular component organization cellular component biogenesis cellular component assembly protein-containing complex organization protein complex oligomerization protein-containing complex assembly response to nutrient levels cellular homeostasis chemical homeostasis response to stimulus homeostatic process intracellular nitrogen homeostasis nitrogen utilization intracellular chemical homeostasis cellular component organization cellular component biogenesis cellular component assembly protein-containing complex organization protein complex oligomerization protein-containing complex assembly protein homooligomerization cellular process cellular component organization or biogenesis glutamine family amino acid biosynthetic process oxoacid metabolic process cellular biosynthetic process organonitrogen compound biosynthetic process amino acid metabolic process organic acid metabolic process organic acid biosynthetic process alpha-amino acid metabolic process carboxylic acid biosynthetic process glutamine family amino acid metabolic process organic substance metabolic process organic substance biosynthetic process small molecule metabolic process glutamine metabolic process organonitrogen compound metabolic process small molecule biosynthetic process cellular metabolic process carboxylic acid metabolic process primary metabolic process L-amino acid biosynthetic process L-amino acid metabolic process proteinogenic amino acid metabolic process amino acid biosynthetic process biosynthetic process proteinogenic amino acid biosynthetic process metabolic process glutamine biosynthetic process alpha-amino acid biosynthetic process	membrane cellular anatomical entity intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR004809	Glutamine synthetase type I	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR008146	Glutamine synthetase, catalytic domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR001637	Glutamine synthetase class-I, adenylation site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR027303	Glutamine synthetase, glycine-rich site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR027302	Glutamine synthetase, N-terminal conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR014746	Glutamine synthetase/guanido kinase, catalytic domain	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR008147	Glutamine synthetase, N-terminal domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR036651	Glutamine synthetase, N-terminal domain superfamily	Homologous Superfamily