Annotations: 2K8Q

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	KOG3247	e2k8qA1	A: beta sandwiches	X: HSP20-like	H: HSP20-like chaperones (From Topology)	T: HSP20-like chaperones	F: KOG3247	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.40.790	Mainly Beta	Sandwich	Immunoglobulin-like		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF21413	SHQ1-like, CS domain (SHQ1-like_CS)	SHQ1-like, CS domain	This domain is found at the N-terminal end of Protein SHQ1 homolog from humans and similar eukaryotic proteins. SHQ1 is a factor required for the biogenesis and assembly of H/ACA small nucleolar ribonucleoparticle (snoRNP), which are essential for ri ...	This domain is found at the N-terminal end of Protein SHQ1 homolog from humans and similar eukaryotic proteins. SHQ1 is a factor required for the biogenesis and assembly of H/ACA small nucleolar ribonucleoparticle (snoRNP), which are essential for ribosomal RNA and telomerase RNA processing and metabolism. This protein contains two domains: an N-terminal CS (named after CHORD-containing proteins and SGT1) or HSP20-like domain (represented by this entry), and a C-terminal region called the Shq1 domain (Pfam:PF04925). The CS domain folds into a compact anti-parallel beta-sandwich made of two beta-sheets with four and three beta-strands, respectively, and a short alpha-helix [1-3].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Protein SHQ1	unfolded protein binding protein binding binding	ribonucleoprotein complex biogenesis box H/ACA snoRNP assembly protein-containing complex organization small nucleolar ribonucleoprotein complex assembly protein-RNA complex assembly cellular component organization cellular component biogenesis protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular process cellular component organization or biogenesis	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle nucleoplasm organelle lumen organelle nuclear lumen

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR007052	CS domain	Domain
A	IPR007009	Shq1, C-terminal domain	Domain
A	IPR048696	SHQ1-like, CS domain	Domain
A	IPR008978	HSP20-like chaperone	Homologous Superfamily
A	IPR039742	Protein Shq1	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.