2JY9

NMR structure of putative tRNA hydrolase domain from Salmonella typhimurium. NorthEast Structural Genomics Consortium target StR220

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	RF-1_N	e2jy9A1	A: a+b two layers	X: dsRBD-like	H: Peptidyl-tRNA hydrolase domain-like (From Topology)	T: Peptidyl-tRNA hydrolase domain-like	F: RF-1_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.160.20	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00472	RF-1 domain (RF-1)	RF-1 domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Putative tRNA hydrolase domain	aminoacyl-tRNA hydrolase activity hydrolase activity, acting on ester bonds catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid carboxylic ester hydrolase activity hydrolase activity catalytic activity, acting on a tRNA catalytic activity translation regulator activity binding organic cyclic compound binding translation regulator activity, nucleic acid binding translation release factor activity nucleic acid binding aminoacyl-tRNA hydrolase activity hydrolase activity, acting on ester bonds catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid carboxylic ester hydrolase activity hydrolase activity catalytic activity, acting on a tRNA catalytic activity translation regulator activity binding organic cyclic compound binding translation regulator activity, nucleic acid binding translation release factor activity nucleic acid binding translation termination factor activity translation factor activity, RNA binding ribonucleoprotein complex binding protein-containing complex binding ribosome binding	cellular biosynthetic process rescue of stalled ribosome organonitrogen compound biosynthetic process cellular component organization organic substance metabolic process organelle disassembly organic substance biosynthetic process cellular component organization or biogenesis protein metabolic process cellular component disassembly organonitrogen compound metabolic process ribosome disassembly cellular metabolic process primary metabolic process cellular biosynthetic process rescue of stalled ribosome organonitrogen compound biosynthetic process cellular component organization organic substance metabolic process organelle disassembly organic substance biosynthetic process cellular component organization or biogenesis protein metabolic process cellular component disassembly organonitrogen compound metabolic process ribosome disassembly cellular metabolic process primary metabolic process translation gene expression macromolecule biosynthetic process organelle organization biosynthetic process translational elongation cellular process metabolic process macromolecule metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR000352	Peptide chain release factor class I	Domain
A	IPR045853	Peptide chain release factor class I superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.