2J5I

Crystal Structure of Hydroxycinnamoyl-CoA Hydratase-Lyase

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2j5ia_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Bd2j5ib_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Cd2j5ic_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Dd2j5id_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Ed2j5ie_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Fd2j5if_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Gd2j5ig_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Hd2j5ih_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Jd2j5ij_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Kd2j5ik_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Ld2j5il_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)
Id2j5ii_ Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase automated matches automated matches (Pseudomonas fluorescens ) [TaxId: 294 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
CSCOP2 FamilyCrotonase-like8067192 4000036 SCOP2 (2022-06-29)
CSCOP2 SuperfamilyClpP/crotonase8067193 3000033 SCOP2 (2022-06-29)
DSCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
JSCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
KSCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
LSCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)
ISCOP2B SuperfamilyClpP/crotonase8067193 3000033 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF00378e2j5iA1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
BPF00378e2j5iB1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
CPF00378e2j5iC1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
DPF00378e2j5iD1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
EPF00378e2j5iE1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
FPF00378e2j5iF1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
GPF00378e2j5iG1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
HPF00378e2j5iH1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
JPF00378e2j5iJ1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
KPF00378e2j5iK1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
LPF00378e2j5iL1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)
IPF00378e2j5iI1 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: PF00378ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
A6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
B3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
B6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
C3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
C6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
D3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
D6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
E3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
E6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
F3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
F6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
G3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
G6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
H3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
H6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
J3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
J6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
K3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
K6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
L3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
L6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)
I3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase Chain A, domain 1CATH (4.3.0)
I6.10.250.2850 Special Helix non-globular Single alpha-helices involved in coiled-coils or other helix-helix interfaces CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00378Enoyl-CoA hydratase/isomerase (ECH_1)Enoyl-CoA hydratase/isomeraseThis family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.Domain
B, C, D, E, F
PF00378Enoyl-CoA hydratase/isomerase (ECH_1)Enoyl-CoA hydratase/isomeraseThis family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.Domain
PF00378Enoyl-CoA hydratase/isomerase (ECH_1)Enoyl-CoA hydratase/isomeraseThis family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
P-HYDROXYCINNAMOYL COA HYDRATASE/LYASE - -
B, C, D, E, F
P-HYDROXYCINNAMOYL COA HYDRATASE/LYASE - -
P-HYDROXYCINNAMOYL COA HYDRATASE/LYASE - -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR001753Enoyl-CoA hydratase/isomeraseFamily
IPR029045ClpP/crotonase-like domain superfamilyHomologous Superfamily
IPR018376Enoyl-CoA hydratase/isomerase, conserved siteConserved Site
B, C, D, E, F
IPR001753Enoyl-CoA hydratase/isomeraseFamily
B, C, D, E, F
IPR029045ClpP/crotonase-like domain superfamilyHomologous Superfamily
B, C, D, E, F
IPR018376Enoyl-CoA hydratase/isomerase, conserved siteConserved Site
IPR001753Enoyl-CoA hydratase/isomeraseFamily
IPR029045ClpP/crotonase-like domain superfamilyHomologous Superfamily
IPR018376Enoyl-CoA hydratase/isomerase, conserved siteConserved Site