Annotations: 2J49

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2j49a1	Alpha and beta proteins (a+b)	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	Taf5 N-terminal domain-like	TAF5 subunit of TFIID	BAKER'S YEAST (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Taf5 N-terminal domain-like	8022241	4002620	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Taf5 N-terminal domain-like	8034621	3001495	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	TFIID_NTD2	e2j49A1	A: alpha superhelices	X: Taf5 N-terminal domain-like (From Topology)	H: Taf5 N-terminal domain-like (From Topology)	T: Taf5 N-terminal domain-like	F: TFIID_NTD2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.25.40.500	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	TFIID subunit TAF5, NTD2 domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF04494	WD40 associated region in TFIID subunit, NTD2 domain (TFIID_NTD2)	WD40 associated region in TFIID subunit, NTD2 domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5	protein-containing complex binding chromatin binding binding molecular adaptor activity protein binding ubiquitin binding ubiquitin-like protein binding identical protein binding	cellular biosynthetic process RNA metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process transcription by RNA polymerase II organic substance metabolic process organic substance biosynthetic process transcription initiation at RNA polymerase II promoter cellular metabolic process primary metabolic process nucleobase-containing compound biosynthetic process gene expression cellular biosynthetic process RNA metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process transcription by RNA polymerase II organic substance metabolic process organic substance biosynthetic process transcription initiation at RNA polymerase II promoter cellular metabolic process primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process DNA-templated transcription initiation organic cyclic compound metabolic process biosynthetic process organic cyclic compound biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of cellular process regulation of primary metabolic process regulation of RNA metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of transcription by RNA polymerase II regulation of biosynthetic process regulation of biological process biological regulation regulation of cellular metabolic process regulation of macromolecule metabolic process regulation of cellular biosynthetic process regulation of gene expression regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process positive regulation of macromolecule biosynthetic process positive regulation of metabolic process positive regulation of macromolecule metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of transcription by RNA polymerase II positive regulation of RNA metabolic process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of cellular process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process protein-DNA complex organization cellular component organization protein-containing complex organization chromatin organization cellular component organization or biogenesis	protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein-containing complex intracellular anatomical structure catalytic complex peptidase complex protein-DNA complex chromatin chromosome transferase complex cellular anatomical entity histone acetyltransferase complex acetyltransferase complex intracellular organelle organelle intracellular non-membrane-bounded organelle protein acetyltransferase complex SAGA-type complex SAGA complex intracellular protein-containing complex non-membrane-bounded organelle RNA polymerase II transcription regulator complex membrane-bounded organelle RNA polymerase II, holoenzyme nucleus membrane-enclosed lumen nuclear protein-containing complex transcription regulator complex intracellular organelle lumen nucleoplasm intracellular membrane-bounded organelle transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex organelle lumen RNA polymerase complex transcription factor TFIID complex DNA-directed RNA polymerase complex nuclear lumen SLIK (SAGA-like) complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR007582	TFIID subunit TAF5, NTD2 domain	Domain
A	IPR019775	WD40 repeat, conserved site	Conserved Site
A	IPR037264	TFIID subunit TAF5, NTD2 domain superfamily	Homologous Superfamily
A	IPR036322	WD40-repeat-containing domain superfamily	Homologous Superfamily
A	IPR001680	WD40 repeat	Repeat
A	IPR020472	G-protein beta WD-40 repeat	Repeat
A	IPR006594	LIS1 homology motif	Conserved Site
A	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.