2HSJ

The structure of a putative platelet activating factor from Streptococcus pneumonia.

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2hsja1	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Acetylhydrolase	Uncharacterized protein SP1450	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
B	d2hsjb2	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Acetylhydrolase	Uncharacterized protein SP1450	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
B	d2hsjb3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
C	d2hsjc2	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Acetylhydrolase	Uncharacterized protein SP1450	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
C	d2hsjc3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
D	d2hsjd2	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Acetylhydrolase	Uncharacterized protein SP1450	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
D	d2hsjd3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Acetylhydrolase	8021890	4003709	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	SGNH hydrolase-like	8034270	3001315	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	SGNH hydrolase-like	8034270	3001315	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	SGNH hydrolase-like	8034270	3001315	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	SGNH hydrolase-like	8034270	3001315	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Lipase_GDSL_2	e2hsjA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: Lipase_GDSL_2	ECOD (1.6)
B	Lipase_GDSL_2	e2hsjB1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: Lipase_GDSL_2	ECOD (1.6)
C	Lipase_GDSL_2	e2hsjC1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: Lipase_GDSL_2	ECOD (1.6)
D	Lipase_GDSL_2	e2hsjD1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: Lipase_GDSL_2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)
B	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)
C	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)
D	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF13472	GDSL-like Lipase/Acylhydrolase family (Lipase_GDSL_2)	GDSL-like Lipase/Acylhydrolase family	This family of presumed lipases and related enzymes are similar to Pfam:PF00657.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Putative platelet activating factor	cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR013830	SGNH hydrolase-type esterase domain	Domain
A, B, C, D	IPR036514	SGNH hydrolase superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.