2H9X

NMR structure for the CgNa toxin from the sea anemone Condylactis gigantea

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2h9xa_	Small proteins	Defensin-like	Defensin-like	Defensin	automated matches	(Condylactis gigantea ) [TaxId: 47073 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Defensin	8070368	4003358	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Defensin-like	8070369	3000681	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00706	e2h9xA1	A: few secondary structure elements	X: Defensin-like	H: Defensin-related	T: Defensin-related	F: PF00706	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.20.20.10	Mainly Beta	Single Sheet	Anthopleurin-A	Anthopleurin-A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00706	Anenome neurotoxin (Toxin_4)	Anenome neurotoxin	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Toxin CgNa	channel regulator activity ion channel regulator activity molecular function regulator activity sodium channel regulator activity transporter regulator activity toxin activity	-	extracellular region cellular anatomical entity cell periphery intracellular organelle cell cortex intracellular anatomical structure organelle intracellular non-membrane-bounded organelle nematocyst cytoplasm non-membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR023355	Myotoxin/Anemone neurotoxin domain superfamily	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A	HYP	Parent Component: PRO RESID: AA0030 PSI-MOD : 4-hydroxy-L-proline MOD:00039

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.