2H1H

E. coli heptosyltransferase WaaC with ADP-2-deoxy-2-fluoro heptose

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Glyco_transf_9_C	e2h1hA1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_9_C	ECOD (1.6)
A	Glyco_transf_9_N	e2h1hA2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_9_N	ECOD (1.6)
B	Glyco_transf_9_C	e2h1hB1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_9_C	ECOD (1.6)
B	Glyco_transf_9_N	e2h1hB2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_9_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
B	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01075	Glycosyltransferase family 9 (heptosyltransferase) (Glyco_transf_9)	Glycosyltransferase family 9 (heptosyltransferase)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Lipopolysaccharide heptosyltransferase 1	lipopolysaccharide heptosyltransferase activity glycosyltransferase activity transferase activity catalytic activity ADP-heptose-lipopolysaccharide heptosyltransferase activity	lipopolysaccharide biosynthetic process cellular biosynthetic process lipid biosynthetic process carbohydrate derivative metabolic process lipopolysaccharide metabolic process lipopolysaccharide core region biosynthetic process organic substance metabolic process polysaccharide metabolic process oligosaccharide biosynthetic process organic substance biosynthetic process carbohydrate derivative biosynthetic process carbohydrate metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process lipopolysaccharide biosynthetic process cellular biosynthetic process lipid biosynthetic process carbohydrate derivative metabolic process lipopolysaccharide metabolic process lipopolysaccharide core region biosynthetic process organic substance metabolic process polysaccharide metabolic process oligosaccharide biosynthetic process organic substance biosynthetic process carbohydrate derivative biosynthetic process carbohydrate metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process oligosaccharide metabolic process cellular metabolic process liposaccharide metabolic process primary metabolic process lipopolysaccharide core region metabolic process macromolecule biosynthetic process biosynthetic process metabolic process cellular process macromolecule metabolic process lipid metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol cell periphery plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR011908	Lipopolysaccharide heptosyltransferase I	Family
A, B	IPR002201	Glycosyl transferase, family 9	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B	OPM	Monotopic/peripheral	Alpha/Beta monotopic/peripheral	UDP-Glycosyltransferase/glycogen phosphorylase	Glycosyltransferase family 9

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.