2GO7

CRYSTAL STRUCTURE OF A HYDROLASE FROM HALOACID DEHALOGENASE-LIKE FAMILY (SP_2064) FROM STREPTOCOCCUS PNEUMONIAE TIGR4 AT 2.10 A RESOLUTION

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2go7a1	Alpha and beta proteins (a/b)	HAD-like	HAD-like	beta-Phosphoglucomutase-like	Hypothetical protein SP2064	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
B	d2go7b_	Alpha and beta proteins (a/b)	HAD-like	HAD-like	beta-Phosphoglucomutase-like	Hypothetical protein SP2064	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
C	d2go7c2	Alpha and beta proteins (a/b)	HAD-like	HAD-like	beta-Phosphoglucomutase-like	Hypothetical protein SP2064	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
C	d2go7c3	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
D	d2go7d_	Alpha and beta proteins (a/b)	HAD-like	HAD-like	beta-Phosphoglucomutase-like	Hypothetical protein SP2064	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	beta-Phosphoglucomutase-like	8029599	4002304	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	HAD-like	8041978	3001890	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	HAD-like	8041978	3001890	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	HAD-like	8041978	3001890	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	HAD-like	8041978	3001890	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	HAD_YsbA-like	e2go7A1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: HAD-like	F: HAD_YsbA-like	ECOD (1.6)
B	HAD_YsbA-like	e2go7B1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: HAD-like	F: HAD_YsbA-like	ECOD (1.6)
C	HAD_YsbA-like	e2go7C1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: HAD-like	F: HAD_YsbA-like	ECOD (1.6)
D	HAD_YsbA-like	e2go7D1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: HAD-like	F: HAD_YsbA-like	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HAD superfamily/HAD-like	CATH (4.3.0)
A	1.10.150.240	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)
B	3.40.50.1000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HAD superfamily/HAD-like	CATH (4.3.0)
B	1.10.150.240	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)
C	3.40.50.1000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HAD superfamily/HAD-like	CATH (4.3.0)
C	1.10.150.240	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)
D	3.40.50.1000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HAD superfamily/HAD-like	CATH (4.3.0)
D	1.10.150.240	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF13419	Haloacid dehalogenase-like hydrolase (HAD_2)	Haloacid dehalogenase-like hydrolase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	hydrolase, haloacid dehalogenase-like family	hydrolase activity catalytic activity cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR036412	HAD-like superfamily	Homologous Superfamily
A, B, C, D	IPR023214	HAD superfamily	Homologous Superfamily
A, B, C, D	IPR006439	HAD hydrolase, subfamily IA	Family
A, B, C, D	IPR041492	Haloacid dehalogenase-like hydrolase	Family
A, B, C, D	IPR023198	Phosphoglycolate phosphatase-like, domain 2	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.