2FTC

Structural Model for the Large Subunit of the Mammalian Mitochondrial Ribosome

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
D [auth C]	SCOP2 Family	Ribosomal protein L3	8089155	4002103	SCOP2 (2022-06-29)
D [auth C]	SCOP2 Superfamily	Translational proteins	8089156	3000811	SCOP2 (2022-06-29)
E [auth D]	SCOP2 Family	Ribosomal protein L4	8080711	4003628	SCOP2 (2022-06-29)
E [auth D]	SCOP2 Superfamily	Ribosomal protein L4	8080712	3001146	SCOP2 (2022-06-29)
I [auth H]	SCOP2 Family	Ribosomal protein L13	8082408	4003623	SCOP2 (2022-06-29)
I [auth H]	SCOP2 Superfamily	Ribosomal protein L13	8082409	3001134	SCOP2 (2022-06-29)
K [auth J]	SCOP2 Family	Prokaryotic ribosomal protein L17	8089009	4003526	SCOP2 (2022-06-29)
K [auth J]	SCOP2 Superfamily	Prokaryotic ribosomal protein L17	8089010	3000995	SCOP2 (2022-06-29)
N [auth M]	SCOP2 Family	Ribosomal protein L22	8081523	4001212	SCOP2 (2022-06-29)
N [auth M]	SCOP2 Superfamily	Ribosomal protein L22	8081524	3001078	SCOP2 (2022-06-29)
Q [auth P]	SCOP2 Family	Ribosomal protein L33p	8075057	4000511	SCOP2 (2022-06-29)
Q [auth P]	SCOP2 Superfamily	Zn-binding ribosomal proteins	8075058	3001320	SCOP2 (2022-06-29)
M [auth L]	SCOP2 Family	Ribosomal protein L20	8075013	4001930	SCOP2 (2022-06-29)
M [auth L]	SCOP2 Superfamily	Ribosomal protein L20	8075014	3000563	SCOP2 (2022-06-29)
O [auth N]	SCOP2 Family	Ribosomal proteins L24p and L21e	8082520	4001752	SCOP2 (2022-06-29)
O [auth N]	SCOP2 Superfamily	Translation proteins SH3-like KOW motif containing domain	8082521	3000334	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
D [auth C]	PF00297	e2ftcC1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF00297	ECOD (1.6)
E [auth D]	PF00573	e2ftcD1	A: a/b three-layered sandwiches	X: Ribosomal protein L4 (From Topology)	H: Ribosomal protein L4 (From Topology)	T: Ribosomal protein L4	F: PF00573	ECOD (1.6)
F [auth E]	PF16320	e2ftcE2	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: PF16320	ECOD (1.6)
F [auth E]	PF00542	e2ftcE1	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: PF00542	ECOD (1.6)
G [auth F]	PF16320	e2ftcF1	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: PF16320	ECOD (1.6)
G [auth F]	PF00542	e2ftcF2	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: PF00542	ECOD (1.6)
H [auth G]	PF00298	e2ftcG2	A: alpha arrays	X: HTH	H: HTH	T: Ribosomal protein L11, C-terminal domain	F: PF00298	ECOD (1.6)
H [auth G]	PF03946	e2ftcG3	A: a+b two layers	X: Ribosomal protein L11/L12e N-terminal domain-like	H: Ribosomal protein L11/L12e N-terminal domain (From Topology)	T: Ribosomal protein L11/L12e N-terminal domain	F: PF03946	ECOD (1.6)
I [auth H]	PF00572	e2ftcH1	A: a/b three-layered sandwiches	X: Ribosomal protein L13/L15p/L18e/L32e	H: Ribosomal protein L13 and L16-A (From Topology)	T: Ribosomal protein L13 and L16-A	F: PF00572	ECOD (1.6)
K [auth J]	PF01196	e2ftcJ1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Prokaryotic ribosomal protein L17 (From Topology)	T: Prokaryotic ribosomal protein L17	F: PF01196	ECOD (1.6)
L [auth K]	PF01245	e2ftcK1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF01245	ECOD (1.6)
N [auth M]	PF00237	e2ftcM1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Ribosomal protein L22 (From Topology)	T: Ribosomal protein L22	F: PF00237	ECOD (1.6)
P [auth O]	PF01016	e2ftcO1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Ribosomal L27 protein	F: PF01016	ECOD (1.6)
Q [auth P]	PF00471	e2ftcP1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF00471	ECOD (1.6)
R [auth Q]	PF00468	e2ftcQ1	A: extended segments	X: 50S ribosomal protein L34 (From Topology)	H: 50S ribosomal protein L34 (From Topology)	T: 50S ribosomal protein L34	F: PF00468	ECOD (1.6)
M [auth L]	PF00453	e2ftcL1	A: alpha arrays	X: PABP domain-like	H: Ribosomal protein L20 (From Topology)	T: Ribosomal protein L20	F: PF00453	ECOD (1.6)
O [auth N]	PF00467,PF17136	e2ftcN1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF00467,PF17136	ECOD (1.6)
B [auth A]	F_UNCLASSIFIED	e2ftcA2	A: a+b two layers	X: a+b domain in Ribosomal protein L1 (From Topology)	H: a+b domain in Ribosomal protein L1 (From Topology)	T: a+b domain in Ribosomal protein L1	F: F_UNCLASSIFIED	ECOD (1.6)
J [auth I]	PF00252	e2ftcI1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Ribosomal protein L10e	F: PF00252	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
D [auth C]	PF00297	Ribosomal protein L3 (Ribosomal_L3)	Ribosomal protein L3	-	Family
E [auth D]	PF00573	Ribosomal protein L4/L1 family (Ribosomal_L4)	Ribosomal protein L4/L1 family	-	Family
F [auth E], G [auth F]	PF16320	Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)	Ribosomal protein L7/L12 dimerisation domain	This is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1].	Domain
F [auth E], G [auth F]	PF00542	Ribosomal protein L7/L12 C-terminal domain (Ribosomal_L12)	Ribosomal protein L7/L12 C-terminal domain	-	Domain
H [auth G]	PF03946	Ribosomal protein L11, N-terminal domain (Ribosomal_L11_N)	Ribosomal protein L11, N-terminal domain	The N-terminal domain of Ribosomal protein L11 adopts an alpha/beta fold and is followed by the RNA binding C-terminal domain.	Domain
H [auth G]	PF00298	Ribosomal protein L11, RNA binding domain (Ribosomal_L11)	Ribosomal protein L11, RNA binding domain	-	Domain
I [auth H]	PF00572	Ribosomal protein L13 (Ribosomal_L13)	Ribosomal protein L13	-	Family
K [auth J]	PF01196	Ribosomal protein L17 (Ribosomal_L17)	Ribosomal protein L17	-	Family
L [auth K]	PF01245	Ribosomal protein L19 (Ribosomal_L19)	Ribosomal protein L19	-	Family
N [auth M]	PF00237	Ribosomal protein L22p/L17e (Ribosomal_L22)	Ribosomal protein L22p/L17e	This family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes.	Domain
P [auth O]	PF01016	Ribosomal L27 protein (Ribosomal_L27)	Ribosomal L27 protein	-	Family
Q [auth P]	PF00471	Ribosomal protein L33 (Ribosomal_L33)	Ribosomal protein L33	-	Family
R [auth Q]	PF00468	Ribosomal protein L34 (Ribosomal_L34)	Ribosomal protein L34	-	Family
M [auth L]	PF00453	Ribosomal protein L20 (Ribosomal_L20)	Ribosomal protein L20	-	Family
O [auth N]	PF17136	Ribosomal proteins 50S L24/mitochondrial 39S L24 (ribosomal_L24)	Ribosomal proteins 50S L24/mitochondrial 39S L24	-	Family
O [auth N]	PF00467	KOW motif (KOW)	KOW motif	-	Family
B [auth A]	PF00687	Ribosomal protein L1p/L10e family (Ribosomal_L1)	Ribosomal protein L1p/L10e family	This family includes prokaryotic L1 and eukaryotic L10.	Domain
C [auth B]	PF03947	Ribosomal Proteins L2, C-terminal domain (Ribosomal_L2_C)	Ribosomal Proteins L2, C-terminal domain	-	Domain
C [auth B]	PF00181	Ribosomal Proteins L2, RNA binding domain (Ribosomal_L2)	Ribosomal Proteins L2, RNA binding domain	-	Domain
J [auth I]	PF00252	Ribosomal protein L16p/L10e (Ribosomal_L16)	Ribosomal protein L16p/L10e	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
D [auth C]	Mitochondrial 39S ribosomal protein L3	structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
E [auth D]	mitochondrial ribosomal protein L4 isoform a	structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
F [auth E], G [auth F]	39S ribosomal protein L12, mitochondrial	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome	regulation of cellular process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological process positive regulation of nucleobase-containing compound metabolic process cellular metabolic process primary metabolic process regulation of cellular process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological process positive regulation of nucleobase-containing compound metabolic process cellular metabolic process primary metabolic process regulation of cellular metabolic process positive regulation of RNA metabolic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of DNA-templated transcription regulation of metabolic process positive regulation of DNA-templated transcription cellular biosynthetic process positive regulation of biological process RNA metabolic process positive regulation of cellular metabolic process RNA biosynthetic process nucleic acid biosynthetic process organic substance metabolic process positive regulation of biosynthetic process positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process biological regulation regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process positive regulation of RNA biosynthetic process cellular process positive regulation of cellular biosynthetic process mitochondrial gene expression mitochondrial transcription mitochondrial RNA metabolic process organonitrogen compound metabolic process organonitrogen compound biosynthetic process translation protein metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
H [auth G]	39S ribosomal protein L11, mitochondrial	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
I [auth H]	39S ribosomal protein L13, mitochondrial	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome	regulation of cellular process cellular biosynthetic process organonitrogen compound biosynthetic process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of cellular process cellular biosynthetic process organonitrogen compound biosynthetic process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process organonitrogen compound metabolic process cellular metabolic process regulation of protein metabolic process negative regulation of metabolic process biological regulation regulation of cellular metabolic process primary metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process negative regulation of cellular biosynthetic process regulation of cellular biosynthetic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process regulation of translation negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
K [auth J]	Mitochondrial ribosomal protein L17	structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
L [auth K]	39S ribosomal protein L19, mitochondrial	structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
N [auth M]	mitochondrial ribosomal protein L22 isoform a	structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle mitochondrial membrane organelle inner membrane membrane mitochondrial inner membrane organelle envelope mitochondrial envelope membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle mitochondrial membrane organelle inner membrane membrane mitochondrial inner membrane organelle envelope mitochondrial envelope organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
P [auth O]	Mitochondrial 39S ribosomal protein L27	structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
Q [auth P]	mitochondrial ribosomal protein L33 isoform a	structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle mitochondrial membrane organelle inner membrane membrane mitochondrial inner membrane organelle envelope mitochondrial envelope membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle mitochondrial membrane organelle inner membrane membrane mitochondrial inner membrane organelle envelope mitochondrial envelope organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
R [auth Q]	39S ribosomal protein L34, mitochondrial	structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
A [auth R]	Mitochondrial 16S ribosomal RNA	-	-	-
M [auth L]	MRPL20 protein	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
O [auth N]	mitochondrial ribosomal protein L24	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle mitochondrial membrane organelle inner membrane membrane mitochondrial inner membrane organelle envelope mitochondrial envelope membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle mitochondrial membrane organelle inner membrane membrane mitochondrial inner membrane organelle envelope mitochondrial envelope organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle
B [auth A]	Mitochondrial ribosomal protein L1	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex ribosomal subunit ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome large ribosomal subunit non-membrane-bounded organelle
C [auth B]	mitochondrial ribosomal protein L2	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process mitochondrial translation cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process mitochondrial gene expression gene expression translation macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process organonitrogen compound metabolic process mitochondrial translation cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process mitochondrial gene expression gene expression translation macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process macromolecule metabolic process protein metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle nucleus nucleoplasm nuclear lumen
J [auth I]	Mitochondrial ribosomal protein L16	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	organonitrogen compound metabolic process mitochondrial translation cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process mitochondrial gene expression gene expression translation macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process organonitrogen compound metabolic process mitochondrial translation cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process mitochondrial gene expression gene expression translation macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process macromolecule metabolic process protein metabolic process	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane cellular anatomical entity intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope mitochondrial envelope organelle cytoplasm organelle membrane protein-containing complex mitochondrial large ribosomal subunit membrane-enclosed lumen mitochondrial matrix intracellular organelle lumen ribosomal subunit organellar ribosome ribosome large ribosomal subunit organellar large ribosomal subunit non-membrane-bounded organelle mitochondrial protein-containing complex mitochondrial ribosome organelle lumen ribonucleoprotein complex intracellular non-membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
D [auth C]	IPR019926	Large ribosomal subunit protein uL3, conserved site	Conserved Site
D [auth C]	IPR019927	Large ribosomal subunit protein uL3, bacterial/organelle-type	Family
D [auth C]	IPR009000	Translation protein, beta-barrel domain superfamily	Homologous Superfamily
D [auth C]	IPR000597	Large ribosomal subunit protein uL3	Family
E [auth D]	IPR013005	Large ribosomal subunit protein uL4-like	Family
E [auth D]	IPR002136	Large ribosomal subunit protein uL4	Family
E [auth D]	IPR023574	Large ribosomal subunit protein uL4 domain superfamily	Homologous Superfamily
F [auth E], G [auth F]	IPR013823	Large ribosomal subunit protein bL12, C-terminal	Domain
F [auth E], G [auth F]	IPR008932	Large ribosomal subunit protein bL12, oligomerization	Domain
F [auth E], G [auth F]	IPR036235	Large ribosomal subunit protein bL12, oligomerization domain superfamily	Homologous Superfamily
F [auth E], G [auth F]	IPR014719	Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like	Homologous Superfamily
F [auth E], G [auth F]	IPR000206	Large ribosomal subunit protein bL12	Family
H [auth G]	IPR020783	Large ribosomal subunit protein uL11, C-terminal	Domain
H [auth G]	IPR000911	Ribosomal protein uL11	Family
H [auth G]	IPR036769	Large ribosomal subunit protein uL11, C-terminal domain superfamily	Homologous Superfamily
H [auth G]	IPR006519	Large ribosomal subunit protein uL11, bacterial-type	Family
H [auth G]	IPR020784	Large ribosomal subunit protein uL11, N-terminal	Domain
H [auth G]	IPR036796	Large ribosomal subunit protein uL11, N-terminal domain superfamily	Homologous Superfamily
I [auth H]	IPR023563	Large ribosomal subunit protein uL13, conserved site	Conserved Site
I [auth H]	IPR005822	Large ribosomal subunit protein uL13	Family
I [auth H]	IPR036899	Large ribosomal subunit protein uL13 superfamily	Homologous Superfamily
I [auth H]	IPR005823	Large ribosomal subunit protein uL13, bacterial-type	Family
K [auth J]	IPR036373	Large ribosomal subunit protein bL17 superfamily	Homologous Superfamily
K [auth J]	IPR000456	Large ribosomal subunit protein bL17	Family
L [auth K]	IPR001857	Large ribosomal subunit protein bL19	Family
L [auth K]	IPR038657	Large ribosomal subunit protein bL19 superfamily	Homologous Superfamily
L [auth K]	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
N [auth M]	IPR047867	Large ribosomal subunit protein uL22, bacterial/organelle-type	Family
N [auth M]	IPR036394	Ribosomal protein uL22 superfamily	Homologous Superfamily
N [auth M]	IPR001063	Large ribosomal subunit protein uL22	Family
P [auth O]	IPR001684	Large ribosomal subunit protein bL27	Family
Q [auth P]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
Q [auth P]	IPR038584	Large ribosomal subunit protein bL33 superfamily	Homologous Superfamily
Q [auth P]	IPR001705	Large ribosomal subunit protein bL33	Family
R [auth Q]	IPR000271	Large ribosomal subunit protein bL34	Family
M [auth L]	IPR035566	Ribosomal protein bL20, C-terminal	Homologous Superfamily
M [auth L]	IPR005813	Large ribosomal subunit protein bL20	Family
O [auth N]	IPR003256	Large ribosomal subunit protein uL24	Family
O [auth N]	IPR041988	Large ribosomal subunit protein uL24, KOW domain	Domain
O [auth N]	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
O [auth N]	IPR005824	KOW	Domain
O [auth N]	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
O [auth N]	IPR005825	Large ribosomal subunit protein uL24, conserved site	Conserved Site
B [auth A]	IPR005879	Large ribosomal subunit protein uL1, mitochondrial	Family
B [auth A]	IPR016095	Large ribosomal subunit protein uL1, 3-layer alpha/beta-sandwich domain	Homologous Superfamily
B [auth A]	IPR023674	Ribosomal protein uL1-like	Homologous Superfamily
B [auth A]	IPR028364	Ribosomal protein uL1/ribosomal biogenesis protein	Family
C [auth B]	IPR022669	Large ribosomal subunit protein uL2, C-terminal	Domain
C [auth B]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
C [auth B]	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
C [auth B]	IPR022666	Large ribosomal subunit protein uL2, RNA-binding domain	Domain
C [auth B]	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
C [auth B]	IPR002171	Large ribosomal subunit protein uL2	Family
J [auth I]	IPR036920	Large ribosomal subunit protein uL16 superfamily	Homologous Superfamily
J [auth I]	IPR000114	Large ribosomal subunit protein uL16, bacterial-type	Family
J [auth I]	IPR016180	Large ribosomal subunit protein uL16 domain	Domain
J [auth I]	IPR047873	Large ribosomal subunit protein uL16	Family