Annotations: 2EBO

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2eboa_	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	Core structure of Ebo gp2	(Ebola virus - Mayinga, Zaire, 1976 ) [TaxId: 128952 ],	SCOPe (2.08)
B	d2ebob_	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	Core structure of Ebo gp2	(Ebola virus - Mayinga, Zaire, 1976 ) [TaxId: 128952 ],	SCOPe (2.08)
C	d2eboc_	Coiled coil proteins	Stalk segment of viral fusion proteins	Virus ectodomain	Virus ectodomain	Core structure of Ebo gp2	(Ebola virus - Mayinga, Zaire, 1976 ) [TaxId: 128952 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Virus ectodomain	8027256	4003841	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Virus ectodomain	8039635	3001628	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Virus ectodomain	8039635	3001628	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Virus ectodomain	8039635	3001628	SCOP2B (2022-06-29)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.287.210	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
B	1.10.287.210	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
C	1.10.287.210	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	EBOLA VIRUS ENVELOPE GLYCOPROTEIN	binding lipid binding identical protein binding protein binding	viral process fusion of virus membrane with host endosome membrane membrane fusion involved in viral entry into host cell symbiont-mediated perturbation of host defense response suppression by virus of host tetherin activity response to host defenses biological process involved in interspecies interaction between organisms response to stimulus response to other organism response to defenses of other organism modulation by virus of host process response to external stimulus virus-mediated perturbation of host defense response biological process involved in interaction with host viral process fusion of virus membrane with host endosome membrane membrane fusion involved in viral entry into host cell symbiont-mediated perturbation of host defense response suppression by virus of host tetherin activity response to host defenses biological process involved in interspecies interaction between organisms response to stimulus response to other organism response to defenses of other organism modulation by virus of host process response to external stimulus virus-mediated perturbation of host defense response biological process involved in interaction with host response to biotic stimulus biological process involved in symbiotic interaction modulation by symbiont of host process response to host response to external biotic stimulus modulation of process of another organism modulation by virus of host cellular process non-lytic viral release viral budding viral life cycle virion assembly exit from host cell viral budding from plasma membrane viral release from host cell symbiont-mediated perturbation of host cellular process symbiont-mediated suppression of host type I interferon-mediated signaling pathway symbiont-mediated suppression of host signal transduction pathway symbiont-mediated suppression of host interferon-mediated signaling pathway cellular process symbiont-mediated perturbation of host signal transduction pathway import into cell receptor-mediated endocytosis of virus by host cell transport establishment of localization vesicle-mediated transport localization symbiont entry into host cell clathrin-dependent endocytosis symbiont entry into host clathrin-dependent endocytosis of virus by host cell receptor-mediated endocytosis endocytosis endocytosis involved in viral entry into host cell transport of virus virion attachment to host cell receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell adhesion of symbiont to host	virion component virion membrane extracellular region cellular anatomical entity host intracellular membrane-bounded organelle host cellular component host intracellular part host cell cytoplasm host cell part host cell endoplasmic reticulum host intracellular region host cell cytoplasm part host intracellular organelle viral membrane virion component virion membrane extracellular region cellular anatomical entity host intracellular membrane-bounded organelle host cellular component host intracellular part host cell cytoplasm host cell part host cell endoplasmic reticulum host intracellular region host cell cytoplasm part host intracellular organelle viral membrane viral envelope membrane microdomain membrane raft membrane host cell plasma membrane host cell membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR014625	Filoviruses glycoprotein	Family
A, B, C	IPR002561	Filoviruses glycoprotein, extracellular domain	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.