2EBA

Crystal structure of the putative glutaryl-CoA dehydrogenase from thermus thermophilus

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2ebaa2	All alpha proteins	Bromodomain-like	Acyl-CoA dehydrogenase C-terminal domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
A	d2ebaa1	Multi-domain proteins (alpha and beta)	Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase NM domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
B [auth C]	d2ebac2	All alpha proteins	Bromodomain-like	Acyl-CoA dehydrogenase C-terminal domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
B [auth C]	d2ebac1	Multi-domain proteins (alpha and beta)	Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase NM domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
C [auth D]	d2ebad2	All alpha proteins	Bromodomain-like	Acyl-CoA dehydrogenase C-terminal domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
C [auth D]	d2ebad1	Multi-domain proteins (alpha and beta)	Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase NM domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
D [auth E]	d2ebae2	All alpha proteins	Bromodomain-like	Acyl-CoA dehydrogenase C-terminal domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
D [auth E]	d2ebae1	Multi-domain proteins (alpha and beta)	Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase NM domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
E [auth F]	d2ebaf2	All alpha proteins	Bromodomain-like	Acyl-CoA dehydrogenase C-terminal domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
E [auth F]	d2ebaf1	Multi-domain proteins (alpha and beta)	Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase NM domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
F [auth G]	d2ebag2	All alpha proteins	Bromodomain-like	Acyl-CoA dehydrogenase C-terminal domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
F [auth G]	d2ebag1	Multi-domain proteins (alpha and beta)	Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase NM domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
G [auth H]	d2ebah2	All alpha proteins	Bromodomain-like	Acyl-CoA dehydrogenase C-terminal domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
G [auth H]	d2ebah1	Multi-domain proteins (alpha and beta)	Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase NM domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
H [auth I]	d2ebai2	All alpha proteins	Bromodomain-like	Acyl-CoA dehydrogenase C-terminal domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
H [auth I]	d2ebai1	Multi-domain proteins (alpha and beta)	Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase NM domain-like	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Acyl-CoA_dh_M	e2ebaA1	A: beta complex topology	X: Acyl-CoA dehydrogenase middle domain-like (From Topology)	H: Acyl-CoA dehydrogenase middle domain-like (From Topology)	T: Acyl-CoA dehydrogenase middle domain-like	F: Acyl-CoA_dh_M	ECOD (1.6)
A	Acyl-CoA_dh_N	e2ebaA2	A: alpha arrays	X: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	H: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase N-terminal domain-like	F: Acyl-CoA_dh_N	ECOD (1.6)
A	Acyl-CoA_dh_1	e2ebaA3	A: alpha bundles	X: Bromodomain-like	H: Acyl-CoA dehydrogenase C-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase C-terminal domain-like	F: Acyl-CoA_dh_1	ECOD (1.6)
B [auth C]	Acyl-CoA_dh_M	e2ebaC1	A: beta complex topology	X: Acyl-CoA dehydrogenase middle domain-like (From Topology)	H: Acyl-CoA dehydrogenase middle domain-like (From Topology)	T: Acyl-CoA dehydrogenase middle domain-like	F: Acyl-CoA_dh_M	ECOD (1.6)
B [auth C]	Acyl-CoA_dh_N	e2ebaC2	A: alpha arrays	X: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	H: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase N-terminal domain-like	F: Acyl-CoA_dh_N	ECOD (1.6)
B [auth C]	Acyl-CoA_dh_1	e2ebaC3	A: alpha bundles	X: Bromodomain-like	H: Acyl-CoA dehydrogenase C-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase C-terminal domain-like	F: Acyl-CoA_dh_1	ECOD (1.6)
C [auth D]	Acyl-CoA_dh_M	e2ebaD1	A: beta complex topology	X: Acyl-CoA dehydrogenase middle domain-like (From Topology)	H: Acyl-CoA dehydrogenase middle domain-like (From Topology)	T: Acyl-CoA dehydrogenase middle domain-like	F: Acyl-CoA_dh_M	ECOD (1.6)
C [auth D]	Acyl-CoA_dh_N	e2ebaD2	A: alpha arrays	X: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	H: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase N-terminal domain-like	F: Acyl-CoA_dh_N	ECOD (1.6)
C [auth D]	Acyl-CoA_dh_1	e2ebaD3	A: alpha bundles	X: Bromodomain-like	H: Acyl-CoA dehydrogenase C-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase C-terminal domain-like	F: Acyl-CoA_dh_1	ECOD (1.6)
D [auth E]	Acyl-CoA_dh_M	e2ebaE1	A: beta complex topology	X: Acyl-CoA dehydrogenase middle domain-like (From Topology)	H: Acyl-CoA dehydrogenase middle domain-like (From Topology)	T: Acyl-CoA dehydrogenase middle domain-like	F: Acyl-CoA_dh_M	ECOD (1.6)
D [auth E]	Acyl-CoA_dh_N	e2ebaE2	A: alpha arrays	X: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	H: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase N-terminal domain-like	F: Acyl-CoA_dh_N	ECOD (1.6)
D [auth E]	Acyl-CoA_dh_1	e2ebaE3	A: alpha bundles	X: Bromodomain-like	H: Acyl-CoA dehydrogenase C-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase C-terminal domain-like	F: Acyl-CoA_dh_1	ECOD (1.6)
E [auth F]	Acyl-CoA_dh_M	e2ebaF1	A: beta complex topology	X: Acyl-CoA dehydrogenase middle domain-like (From Topology)	H: Acyl-CoA dehydrogenase middle domain-like (From Topology)	T: Acyl-CoA dehydrogenase middle domain-like	F: Acyl-CoA_dh_M	ECOD (1.6)
E [auth F]	Acyl-CoA_dh_N	e2ebaF2	A: alpha arrays	X: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	H: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase N-terminal domain-like	F: Acyl-CoA_dh_N	ECOD (1.6)
E [auth F]	Acyl-CoA_dh_1	e2ebaF3	A: alpha bundles	X: Bromodomain-like	H: Acyl-CoA dehydrogenase C-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase C-terminal domain-like	F: Acyl-CoA_dh_1	ECOD (1.6)
F [auth G]	Acyl-CoA_dh_M	e2ebaG1	A: beta complex topology	X: Acyl-CoA dehydrogenase middle domain-like (From Topology)	H: Acyl-CoA dehydrogenase middle domain-like (From Topology)	T: Acyl-CoA dehydrogenase middle domain-like	F: Acyl-CoA_dh_M	ECOD (1.6)
F [auth G]	Acyl-CoA_dh_N	e2ebaG2	A: alpha arrays	X: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	H: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase N-terminal domain-like	F: Acyl-CoA_dh_N	ECOD (1.6)
F [auth G]	Acyl-CoA_dh_1	e2ebaG3	A: alpha bundles	X: Bromodomain-like	H: Acyl-CoA dehydrogenase C-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase C-terminal domain-like	F: Acyl-CoA_dh_1	ECOD (1.6)
G [auth H]	Acyl-CoA_dh_M	e2ebaH1	A: beta complex topology	X: Acyl-CoA dehydrogenase middle domain-like (From Topology)	H: Acyl-CoA dehydrogenase middle domain-like (From Topology)	T: Acyl-CoA dehydrogenase middle domain-like	F: Acyl-CoA_dh_M	ECOD (1.6)
G [auth H]	Acyl-CoA_dh_N	e2ebaH2	A: alpha arrays	X: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	H: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase N-terminal domain-like	F: Acyl-CoA_dh_N	ECOD (1.6)
G [auth H]	Acyl-CoA_dh_1	e2ebaH3	A: alpha bundles	X: Bromodomain-like	H: Acyl-CoA dehydrogenase C-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase C-terminal domain-like	F: Acyl-CoA_dh_1	ECOD (1.6)
H [auth I]	Acyl-CoA_dh_M	e2ebaI1	A: beta complex topology	X: Acyl-CoA dehydrogenase middle domain-like (From Topology)	H: Acyl-CoA dehydrogenase middle domain-like (From Topology)	T: Acyl-CoA dehydrogenase middle domain-like	F: Acyl-CoA_dh_M	ECOD (1.6)
H [auth I]	Acyl-CoA_dh_N	e2ebaI2	A: alpha arrays	X: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	H: Acyl-CoA dehydrogenase N-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase N-terminal domain-like	F: Acyl-CoA_dh_N	ECOD (1.6)
H [auth I]	Acyl-CoA_dh_1	e2ebaI3	A: alpha bundles	X: Bromodomain-like	H: Acyl-CoA dehydrogenase C-terminal domain-like (From Topology)	T: Acyl-CoA dehydrogenase C-terminal domain-like	F: Acyl-CoA_dh_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A	domain 1	CATH (4.3.0)
A	2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A	domain 2	CATH (4.3.0)
A	1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)
B [auth C]	1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A	domain 1	CATH (4.3.0)
B [auth C]	2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A	domain 2	CATH (4.3.0)
B [auth C]	1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)
C [auth D]	1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A	domain 1	CATH (4.3.0)
C [auth D]	2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A	domain 2	CATH (4.3.0)
C [auth D]	1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)
D [auth E]	1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A	domain 1	CATH (4.3.0)
D [auth E]	2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A	domain 2	CATH (4.3.0)
D [auth E]	1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)
E [auth F]	1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A	domain 1	CATH (4.3.0)
E [auth F]	2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A	domain 2	CATH (4.3.0)
E [auth F]	1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)
F [auth G]	1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A	domain 1	CATH (4.3.0)
F [auth G]	2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A	domain 2	CATH (4.3.0)
F [auth G]	1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)
G [auth H]	1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A	domain 1	CATH (4.3.0)
G [auth H]	2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A	domain 2	CATH (4.3.0)
G [auth H]	1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)
H [auth I]	1.10.540.10	Mainly Alpha	Orthogonal Bundle	Butyryl-Coa Dehydrogenase, subunit A	domain 1	CATH (4.3.0)
H [auth I]	2.40.110.10	Mainly Beta	Beta Barrel	Butyryl-CoA Dehydrogenase, subunit A	domain 2	CATH (4.3.0)
H [auth I]	1.20.140.10	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	PF02771	Acyl-CoA dehydrogenase, N-terminal domain (Acyl-CoA_dh_N)	Acyl-CoA dehydrogenase, N-terminal domain	The N-terminal domain of Acyl-CoA dehydrogenase is an all-alpha domain.	Domain
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	PF02770	Acyl-CoA dehydrogenase, middle domain (Acyl-CoA_dh_M)	Acyl-CoA dehydrogenase, middle domain	Central domain of Acyl-CoA dehydrogenase has a beta-barrel fold.	Domain
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	PF00441	Acyl-CoA dehydrogenase, C-terminal domain (Acyl-CoA_dh_1)	Acyl-CoA dehydrogenase, C-terminal domain	C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	Putative glutaryl-CoA dehydrogenase	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor oxidoreductase activity acyl-CoA dehydrogenase activity oxidoreductase activity, acting on the CH-CH group of donors catalytic activity flavin adenine dinucleotide binding binding nucleoside phosphate binding ion binding organic cyclic compound binding anion binding nucleotide binding heterocyclic compound binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	IPR009100	Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily	Homologous Superfamily
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	IPR046373	Acyl-CoA oxidase/dehydrogenase, middle domain superfamily	Homologous Superfamily
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	IPR006091	Acyl-CoA oxidase/dehydrogenase, middle domain	Domain
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	IPR009075	Acyl-CoA dehydrogenase/oxidase, C-terminal	Domain
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	IPR006089	Acyl-CoA dehydrogenase, conserved site	Conserved Site
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	IPR036250	Acyl-CoA dehydrogenase-like, C-terminal	Homologous Superfamily
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	IPR013786	Acyl-CoA dehydrogenase/oxidase, N-terminal	Domain
A, B [auth C], C [auth D], D [auth E], E [auth F], A, B [auth C], C [auth D], D [auth E], E [auth F], F [auth G], G [auth H], H [auth I]	IPR037069	Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily	Homologous Superfamily

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2EBA

Crystal structure of the putative glutaryl-CoA dehydrogenase from thermus thermophilus

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: ECOD Classification ECOD Database Homepage

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage