2D8Q

Solution structure of the MYND domain of the human zinc finger MYND domain-containing protein 10

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Pharos: Disease Associations

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2d8qa1	Small proteins	HIT/MYND zinc finger-like	HIT/MYND zinc finger-like	MYND zinc finger	Zinc finger MYND domain-containing protein 10, ZMYND10	human (Homo sapiens ) [TaxId: 9606 ],	SCOPe (2.08)
A	d2d8qa3	Artifacts	Tags	Tags	Tags	C-terminal Tags	human (Homo sapiens ) [TaxId: 9606 ],	SCOPe (2.08)
A	d2d8qa2	Artifacts	Tags	Tags	Tags	N-terminal Tags	human (Homo sapiens ) [TaxId: 9606 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	HIT/MYND zinc finger-like	8039647	3000530	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01753	e2d8qA1	A: few secondary structure elements	X: Glucocorticoid receptor-like	H: HIT/MYND zinc finger-like (From Topology)	T: HIT/MYND zinc finger-like	F: PF01753	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01753	MYND finger (zf-MYND)	MYND finger	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Zinc finger MYND domain containing protein 10	molecular adaptor activity protein folding chaperone cation binding ion binding binding metal ion binding small molecule binding	positive regulation of organelle organization regulation of cellular process regulation of cellular component organization positive regulation of cellular component organization cell projection organization motile cilium assembly positive regulation of biological process positive regulation of motile cilium assembly plasma membrane bounded cell projection assembly cellular component biogenesis cellular component organization cellular component assembly cilium assembly positive regulation of cell projection organization positive regulation of organelle organization regulation of cellular process regulation of cellular component organization positive regulation of cellular component organization cell projection organization motile cilium assembly positive regulation of biological process positive regulation of motile cilium assembly plasma membrane bounded cell projection assembly cellular component biogenesis cellular component organization cellular component assembly cilium assembly positive regulation of cell projection organization cellular component organization or biogenesis cilium organization positive regulation of cellular process regulation of biological process organelle assembly plasma membrane bounded cell projection organization positive regulation of cellular component biogenesis regulation of cell projection organization regulation of cell projection assembly biological regulation regulation of cellular component biogenesis regulation of organelle organization regulation of plasma membrane bounded cell projection assembly regulation of cilium assembly organelle organization positive regulation of cilium assembly regulation of organelle assembly cellular process regulation of motile cilium assembly cell projection assembly regulation of plasma membrane bounded cell projection organization positive regulation of plasma membrane bounded cell projection assembly positive regulation of organelle assembly axonemal dynein complex assembly protein-containing complex organization microtubule cytoskeleton organization microtubule bundle formation outer dynein arm assembly protein-containing complex assembly microtubule-based process axoneme assembly cytoskeleton organization microtubule-based movement cilium movement protein localization localization cellular localization protein localization to cilium protein localization to organelle cellular macromolecule localization macromolecule localization inner dynein arm assembly	cell periphery apical part of cell membrane plasma membrane plasma membrane region cellular anatomical entity apical plasma membrane intracellular anatomical structure intracellular organelle centrosome microtubule organizing center cytoskeleton centriolar satellite organelle cell periphery apical part of cell membrane plasma membrane plasma membrane region cellular anatomical entity apical plasma membrane intracellular anatomical structure intracellular organelle centrosome microtubule organizing center cytoskeleton centriolar satellite organelle intracellular non-membrane-bounded organelle microtubule cytoskeleton non-membrane-bounded organelle dynein axonemal particle cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR002893	Zinc finger, MYND-type	Domain
A	IPR017333	Uncharacterised conserved protein UCP037948, zinc finger MYND-type	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: O75800	primary ciliary dyskinesia primary ciliary dyskinesia 22 atypical teratoid rhabdoid tumor Kartagener Syndrome bronchiectasis malignant ependymoma primary ciliary dyskinesia 1

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.