Annotations: 2CYU

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2cyua1	All alpha proteins	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	E3-binding domain of dihydrolipoamide succinyltransferase	( ) [TaxId: ], (Escherichia coli O157:H7 ) [TaxId: 83334 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	8027027	4000730	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	8039406	3001183	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02817	e2cyuA1	A: alpha arrays	X: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex (From Topology)	H: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex (From Topology)	T: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	F: PF02817	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF02817	e3 binding domain (E3_binding)	e3 binding domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	2-OXOGLUTARATE DEHYDROGENASE MULTIENZYME COMPLEX	S-succinyltransferase activity catalytic activity, acting on a protein acyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity S-acyltransferase activity dihydrolipoyllysine-residue succinyltransferase activity catalytic activity succinyltransferase activity	aerobic respiration cellular respiration tricarboxylic acid cycle energy derivation by oxidation of organic compounds cellular metabolic process metabolic process cellular process primary metabolic process generation of precursor metabolites and energy nucleoside bisphosphate metabolic process oxoacid metabolic process aspartate family amino acid metabolic process carbohydrate derivative metabolic process amino acid metabolic process aerobic respiration cellular respiration tricarboxylic acid cycle energy derivation by oxidation of organic compounds cellular metabolic process metabolic process cellular process primary metabolic process generation of precursor metabolites and energy nucleoside bisphosphate metabolic process oxoacid metabolic process aspartate family amino acid metabolic process carbohydrate derivative metabolic process amino acid metabolic process acetyl-CoA metabolic process organic acid catabolic process organic acid metabolic process nucleobase-containing compound metabolic process cellular catabolic process carboxylic acid catabolic process L-lysine metabolic process amide catabolic process phosphate-containing compound metabolic process small molecule metabolic process sulfur compound metabolic process thioester metabolic process phosphorus metabolic process amino acid catabolic process nucleoside phosphate metabolic process organonitrogen compound catabolic process nucleotide metabolic process L-amino acid metabolic process organic cyclic compound metabolic process alpha-amino acid catabolic process purine ribonucleotide metabolic process small molecule catabolic process ribose phosphate metabolic process purine nucleoside bisphosphate metabolic process ribonucleoside bisphosphate metabolic process lysine metabolic process catabolic process L-lysine catabolic process alpha-amino acid metabolic process purine nucleotide metabolic process organic substance metabolic process acyl-CoA metabolic process ribonucleotide metabolic process nucleobase-containing small molecule metabolic process amide metabolic process aspartate family amino acid catabolic process organonitrogen compound metabolic process L-lysine catabolic process to acetyl-CoA via saccharopine lysine catabolic process L-amino acid catabolic process carboxylic acid metabolic process purine-containing compound metabolic process proteinogenic amino acid metabolic process proteinogenic amino acid catabolic process L-lysine catabolic process to acetyl-CoA organophosphate metabolic process organic substance catabolic process	protein-containing complex oxoglutarate dehydrogenase complex intracellular anatomical structure catalytic complex oxidoreductase complex tricarboxylic acid cycle heteromeric enzyme complex cytoplasm cellular anatomical entity alpha-ketoacid dehydrogenase complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR001078	2-oxoacid dehydrogenase acyltransferase, catalytic domain	Domain
A	IPR023213	Chloramphenicol acetyltransferase-like domain superfamily	Homologous Superfamily
A	IPR036625	E3-binding domain superfamily	Homologous Superfamily
A	IPR004167	Peripheral subunit-binding domain	Domain
A	IPR006255	Dihydrolipoamide succinyltransferase	Family
A	IPR011053	Single hybrid motif	Homologous Superfamily
A	IPR003016	2-oxo acid dehydrogenase, lipoyl-binding site	Binding Site
A	IPR000089	Biotin/lipoyl attachment	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.