Annotations: 2CRQ

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	IF3_C	e2crqA1	A: a+b two layers	X: IF3-like	H: Translation initiation factor IF3, C-terminal domain (From Topology)	T: Translation initiation factor IF3, C-terminal domain	F: IF3_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.110.10	Alpha Beta	2-Layer Sandwich	Translation Initiation Factor IF3	Translation initiation factor 3 (IF-3), C-terminal domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00707	Translation initiation factor IF-3, C-terminal domain (IF3_C)	Translation initiation factor IF-3, C-terminal domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	mitochondrial translational initiation factor 3	translation regulator activity binding organic cyclic compound binding translation regulator activity, nucleic acid binding nucleic acid binding translation initiation factor activity translation factor activity, RNA binding ribonucleoprotein complex binding protein-containing complex binding ribosomal small subunit binding ribosome binding	organonitrogen compound metabolic process mitochondrial translation cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process mitochondrial translational initiation mitochondrial gene expression gene expression translation macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process organonitrogen compound metabolic process mitochondrial translation cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process mitochondrial translational initiation mitochondrial gene expression gene expression translation macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process translational initiation macromolecule metabolic process protein metabolic process cellular component organization cellular component disassembly organelle organization organelle disassembly ribosome disassembly cellular component organization or biogenesis	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR019815	Translation initiation factor 3, C-terminal	Domain
A	IPR036787	Translation initiation factor 3 (IF-3), N-terminal domain superfamily	Homologous Superfamily
A	IPR001288	Translation initiation factor 3	Family
A	IPR019814	Translation initiation factor 3, N-terminal	Domain
A	IPR036788	Translation initiation factor 3 (IF-3), C-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.