2C55

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	6.10.250.390	Special	Helix non-globular	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)

Chains	Accession	Name	Description	Comments	Source
A	PF08705	Gag protein p6 (Gag_p6)	Gag protein p6	HIV protein p6 contains two late-budding domains (L domains) which are short sequence motifs essential for viral particle release. p6 interacts with the endosomal sorting complex and represents a docking site for several cellular and binding factors ...	HIV protein p6 contains two late-budding domains (L domains) which are short sequence motifs essential for viral particle release. p6 interacts with the endosomal sorting complex and represents a docking site for several cellular and binding factors [1]. The PTAP motif interacts with the cellular budding factor TSG101 [1]. This domain is also found in some chimpanzee immunodeficiency virus (SIV-cpz) proteins.	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	PROTEIN P6	structural molecule activity cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding RNA binding organic cyclic compound binding nucleic acid binding	virion assembly viral process viral budding viral budding via host ESCRT complex viral life cycle	host intracellular membrane-bounded organelle host cellular component host intracellular part host multivesicular body cellular anatomical entity host cell cytoplasm part host intracellular organelle host cell cytoplasm host cell part host cell late endosome host cell endosome host intracellular region membrane virion component host intracellular membrane-bounded organelle host cellular component host intracellular part host multivesicular body cellular anatomical entity host cell cytoplasm part host intracellular organelle host cell cytoplasm host cell part host cell late endosome host cell endosome host intracellular region membrane virion component virion membrane host cell nucleus host cell plasma membrane host cell membrane viral nucleocapsid viral capsid

Chains	Accession	Name	Type
A	IPR000071	Immunodeficiency lentiviral matrix, N-terminal	Domain
A	IPR045345	Retroviral nucleocapsid Gag protein p24, C-terminal domain	Domain
A	IPR036875	Zinc finger, CCHC-type superfamily	Homologous Superfamily
A	IPR001878	Zinc finger, CCHC-type	Domain
A	IPR008919	Retrovirus capsid, N-terminal	Homologous Superfamily
A	IPR010999	Retroviral matrix protein	Homologous Superfamily
A	IPR012344	Matrix protein, lentiviral and alpha-retroviral, N-terminal	Homologous Superfamily
A	IPR014817	Gag protein p6	Domain
A	IPR008916	Retrovirus capsid, C-terminal	Homologous Superfamily