2BYM

Histone fold heterodimer of the Chromatin Accessibility Complex

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2byma_	All alpha proteins	Histone-fold	Histone-fold	TBP-associated factors, TAFs	Chrac-16	FRUIT FLY (Drosophila melanogaster ) [TaxId: 7227 ],	SCOPe (2.08)
C	d2bymc_	All alpha proteins	Histone-fold	Histone-fold	TBP-associated factors, TAFs	Chrac-16	FRUIT FLY (Drosophila melanogaster ) [TaxId: 7227 ],	SCOPe (2.08)
B	d2bymb_	All alpha proteins	Histone-fold	Histone-fold	TBP-associated factors, TAFs	Chrac-14	FRUIT FLY (Drosophila melanogaster ) [TaxId: 7227 ],	SCOPe (2.08)
D	d2bymd_	All alpha proteins	Histone-fold	Histone-fold	TBP-associated factors, TAFs	Chrac-14	FRUIT FLY (Drosophila melanogaster ) [TaxId: 7227 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Core histone-like	8038896	3001387	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Core histone-like	8038896	3001387	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Core histone-like	8038900	3001387	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Core histone-like	8038900	3001387	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CBFD_NFYB_HMF	e2bymA1	A: alpha arrays	X: Histone-like	H: Histone-related	T: Histone	F: CBFD_NFYB_HMF	ECOD (1.6)
C	CBFD_NFYB_HMF	e2bymC1	A: alpha arrays	X: Histone-like	H: Histone-related	T: Histone	F: CBFD_NFYB_HMF	ECOD (1.6)
B	CBFD_NFYB_HMF	e2bymB1	A: alpha arrays	X: Histone-like	H: Histone-related	T: Histone	F: CBFD_NFYB_HMF	ECOD (1.6)
D	CBFD_NFYB_HMF	e2bymD1	A: alpha arrays	X: Histone-like	H: Histone-related	T: Histone	F: CBFD_NFYB_HMF	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.20.10	Mainly Alpha	Orthogonal Bundle	Histone, subunit A	Histone, subunit A	CATH (4.3.0)
C	1.10.20.10	Mainly Alpha	Orthogonal Bundle	Histone, subunit A	Histone, subunit A	CATH (4.3.0)
B	1.10.20.10	Mainly Alpha	Orthogonal Bundle	Histone, subunit A	Histone, subunit A	CATH (4.3.0)
D	1.10.20.10	Mainly Alpha	Orthogonal Bundle	Histone, subunit A	Histone, subunit A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF00808	Histone-like transcription factor (CBF/NF-Y) and archaeal histone (CBFD_NFYB_HMF)	Histone-like transcription factor (CBF/NF-Y) and archaeal histone	This family includes archaebacterial histones and histone like transcription factors from eukaryotes.	Domain
B, D	PF00808	Histone-like transcription factor (CBF/NF-Y) and archaeal histone (CBFD_NFYB_HMF)	Histone-like transcription factor (CBF/NF-Y) and archaeal histone	This family includes archaebacterial histones and histone like transcription factors from eukaryotes.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	CHRAC-16	protein heterodimerization activity protein binding binding protein dimerization activity molecular adaptor activity organic cyclic compound binding nucleic acid binding	protein-DNA complex organization cellular component organization protein-containing complex organization chromatin organization chromatin remodeling cellular process cellular component organization or biogenesis nucleobase-containing compound metabolic process organic cyclic compound metabolic process DNA-templated DNA replication DNA replication organic substance metabolic process metabolic process primary metabolic process protein-DNA complex organization cellular component organization protein-containing complex organization chromatin organization chromatin remodeling cellular process cellular component organization or biogenesis nucleobase-containing compound metabolic process organic cyclic compound metabolic process DNA-templated DNA replication DNA replication organic substance metabolic process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process	membrane-bounded organelle ATPase complex protein-containing complex intracellular anatomical structure catalytic complex protein-DNA complex nucleus nuclear protein-containing complex chromatin chromosome intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle ISWI-type complex membrane-bounded organelle ATPase complex protein-containing complex intracellular anatomical structure catalytic complex protein-DNA complex nucleus nuclear protein-containing complex chromatin chromosome intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle ISWI-type complex organelle intracellular non-membrane-bounded organelle SWI/SNF superfamily-type complex CHRAC non-membrane-bounded organelle
B, D	CHRAC-14	DNA binding protein-containing complex binding binding chromatin binding organic cyclic compound binding nucleic acid binding chromatin DNA binding protein heterodimerization activity protein binding protein dimerization activity	protein-containing complex organization chromosome organization protein-DNA complex assembly CENP-A containing chromatin assembly cellular component organization cellular component biogenesis protein-DNA complex organization organelle organization cellular component assembly chromatin organization protein-containing complex assembly chromatin remodeling cellular process cellular component organization or biogenesis protein-containing complex organization chromosome organization protein-DNA complex assembly CENP-A containing chromatin assembly cellular component organization cellular component biogenesis protein-DNA complex organization organelle organization cellular component assembly chromatin organization protein-containing complex assembly chromatin remodeling cellular process cellular component organization or biogenesis centromere complex assembly chromatin remodeling at centromere cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress DNA-templated DNA replication primary metabolic process DNA metabolic process leading strand elongation nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process DNA strand elongation organic substance metabolic process DNA replication metabolic process DNA strand elongation involved in DNA replication macromolecule metabolic process cellular response to ionizing radiation cellular response to radiation cellular response to environmental stimulus response to ionizing radiation cellular response to gamma radiation response to radiation response to abiotic stimulus cellular response to abiotic stimulus response to gamma radiation regulation of cellular process cellular biosynthetic process negative regulation of biological process negative regulation of cellular metabolic process organic substance biosynthetic process negative regulation of cellular process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process heterochromatin formation epigenetic regulation of gene expression cellular metabolic process negative regulation of metabolic process biological regulation regulation of cellular metabolic process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process negative regulation of cellular biosynthetic process regulation of cellular biosynthetic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process negative regulation of gene expression, epigenetic regulation of macromolecule biosynthetic process regulation of metabolic process	membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex nuclear chromosome chromosome transferase complex intracellular organelle lumen intracellular organelle non-membrane-bounded organelle catalytic complex intracellular membrane-bounded organelle membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus membrane-enclosed lumen nuclear protein-containing complex nuclear chromosome chromosome transferase complex intracellular organelle lumen intracellular organelle non-membrane-bounded organelle catalytic complex intracellular membrane-bounded organelle cellular anatomical entity epsilon DNA polymerase complex DNA polymerase complex transferase complex, transferring phosphorus-containing groups organelle lumen organelle intracellular non-membrane-bounded organelle intracellular protein-containing complex nuclear lumen protein-DNA complex ATAC complex chromatin histone acetyltransferase complex acetyltransferase complex protein acetyltransferase complex SAGA-type complex ATPase complex ISWI-type complex SWI/SNF superfamily-type complex CHRAC

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR003958	Transcription factor CBF/NF-Y/archaeal histone domain	Domain
A, C	IPR009072	Histone-fold	Homologous Superfamily
B, D	IPR009072	Histone-fold	Homologous Superfamily
B, D	IPR003958	Transcription factor CBF/NF-Y/archaeal histone domain	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.