2BL8

1.6 Angstrom crystal structure of EntA-im: a bacterial immunity protein conferring immunity to the antimicrobial activity of the pediocin-like bacteriocin, enterocin A

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2bl8a1	All alpha proteins	Bromodomain-like	Bacteriocin immunity protein-like	EntA-Im	Enterocine A immunity protein, EntA-Im	(Enterococcus faecium ) [TaxId: 1352 ],	SCOPe (2.08)
B	d2bl8b_	All alpha proteins	Bromodomain-like	Bacteriocin immunity protein-like	EntA-Im	automated matches	(Enterococcus faecium ) [TaxId: 1352 ],	SCOPe (2.08)
C	d2bl8c_	All alpha proteins	Bromodomain-like	Bacteriocin immunity protein-like	EntA-Im	automated matches	(Enterococcus faecium ) [TaxId: 1352 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	EntA-Im	8021178	4001243	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Bacteriocin immunity protein-like	8033558	3001211	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Bacteriocin immunity protein-like	8033558	3001211	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Bacteriocin immunity protein-like	8033558	3001211	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	EntA_Immun	e2bl8A1	A: alpha bundles	X: Bromodomain-like	H: Carnobacteriocin B2 immunity protein (From Topology)	T: Carnobacteriocin B2 immunity protein	F: EntA_Immun	ECOD (1.6)
B	EntA_Immun	e2bl8B1	A: alpha bundles	X: Bromodomain-like	H: Carnobacteriocin B2 immunity protein (From Topology)	T: Carnobacteriocin B2 immunity protein	F: EntA_Immun	ECOD (1.6)
C	EntA_Immun	e2bl8C1	A: alpha bundles	X: Bromodomain-like	H: Carnobacteriocin B2 immunity protein (From Topology)	T: Carnobacteriocin B2 immunity protein	F: EntA_Immun	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.1440.50	Mainly Alpha	Up-down Bundle	de novo design (two linked rop proteins)	Ta0600-like	CATH (4.3.0)
B	1.20.1440.50	Mainly Alpha	Up-down Bundle	de novo design (two linked rop proteins)	Ta0600-like	CATH (4.3.0)
C	1.20.1440.50	Mainly Alpha	Up-down Bundle	de novo design (two linked rop proteins)	Ta0600-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF08951	Enterocin A Immunity (EntA_Immun)	Enterocin A Immunity	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	ENTEROCINE A IMMUNITY PROTEIN	-	cellular metabolic process metabolic process cellular process bacteriocin immunity toxin metabolic process secondary metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR015046	Lactococcin-A immunity protein-like	Family
A, B, C	IPR023130	Ta0600-like superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.