2BCW

Coordinates of the N-terminal domain of ribosomal protein L11,C-terminal domain of ribosomal protein L7/L12 and a portion of the G' domain of elongation factor G, as fitted into cryo-em map of an Escherichia coli 70SEF-GGDP*fusidic acid complex

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2bcwa1	Alpha and beta proteins (a+b)	Ribosomal L11/L12e N-terminal domain	Ribosomal L11/L12e N-terminal domain	Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, N-terminal domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
B	d2bcwb1	Alpha and beta proteins (a+b)	ClpS-like	ClpS-like	Ribosomal protein L7/12, C-terminal domain	Ribosomal protein L7/12, C-terminal domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Ribosomal L11/L12e N-terminal domain-like	8035082	3000950	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Ribosomal_L11_N	e2bcwA1	A: a+b two layers	X: Ribosomal protein L11/L12e N-terminal domain-like	H: Ribosomal protein L11/L12e N-terminal domain (From Topology)	T: Ribosomal protein L11/L12e N-terminal domain	F: Ribosomal_L11_N	ECOD (1.6)
B	Ribosomal_L12	e2bcwB1	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: Ribosomal_L12	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF03946	Ribosomal protein L11, N-terminal domain (Ribosomal_L11_N)	Ribosomal protein L11, N-terminal domain	The N-terminal domain of Ribosomal protein L11 adopts an alpha/beta fold and is followed by the RNA binding C-terminal domain.	Domain
A	PF00298	Ribosomal protein L11, RNA binding domain (Ribosomal_L11)	Ribosomal protein L11, RNA binding domain	-	Domain
B	PF00542	Ribosomal protein L7/L12 C-terminal domain (Ribosomal_L12)	Ribosomal protein L7/L12 C-terminal domain	-	Domain
C	PF00009	Elongation factor Tu GTP binding domain (GTP_EFTU)	Elongation factor Tu GTP binding domain	This domain contains a P-loop motif, also found in several other families such as Pfam:PF00071, Pfam:PF00025 and Pfam:PF00063. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	50S ribosomal protein L11	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit non-membrane-bounded organelle
B	50S ribosomal protein L7/L12	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding identical protein binding protein binding protein homodimerization activity protein dimerization activity ribonucleoprotein complex binding protein-containing complex binding ribosome binding structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process cytoplasmic translation metabolic process cellular process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process cytoplasmic translation metabolic process cellular process protein metabolic process macromolecule metabolic process	protein-containing complex intracellular anatomical structure cellular anatomical entity ribosomal subunit intracellular organelle organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome large ribosomal subunit non-membrane-bounded organelle cytoplasm cytosol cytosolic large ribosomal subunit protein-containing complex intracellular anatomical structure cellular anatomical entity ribosomal subunit intracellular organelle organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome large ribosomal subunit non-membrane-bounded organelle cytoplasm cytosol cytosolic large ribosomal subunit cytosolic ribosome
C	Elongation factor G	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding guanyl nucleotide binding nucleotide binding GDP binding guanyl ribonucleotide binding purine ribonucleotide binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding guanyl nucleotide binding nucleotide binding GDP binding guanyl ribonucleotide binding purine ribonucleotide binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding translation regulator activity translation regulator activity, nucleic acid binding translation elongation factor activity nucleic acid binding translation factor activity, RNA binding ribonucleoprotein complex binding protein-containing complex binding ribosome binding GTP binding purine ribonucleoside triphosphate binding pyrophosphatase activity GTPase activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process translational elongation organic substance biosynthetic process metabolic process cellular process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process translational elongation organic substance biosynthetic process metabolic process cellular process macromolecule metabolic process protein metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR020785	Large ribosomal subunit protein uL11, conserved site	Conserved Site
A	IPR020783	Large ribosomal subunit protein uL11, C-terminal	Domain
A	IPR000911	Ribosomal protein uL11	Family
A	IPR036769	Large ribosomal subunit protein uL11, C-terminal domain superfamily	Homologous Superfamily
A	IPR006519	Large ribosomal subunit protein uL11, bacterial-type	Family
A	IPR020784	Large ribosomal subunit protein uL11, N-terminal	Domain
A	IPR036796	Large ribosomal subunit protein uL11, N-terminal domain superfamily	Homologous Superfamily
B	IPR013823	Large ribosomal subunit protein bL12, C-terminal	Domain
B	IPR008932	Large ribosomal subunit protein bL12, oligomerization	Domain
B	IPR036235	Large ribosomal subunit protein bL12, oligomerization domain superfamily	Homologous Superfamily
B	IPR014719	Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like	Homologous Superfamily
B	IPR000206	Large ribosomal subunit protein bL12	Family
C	IPR005517	Translation elongation factor EFG/EF2, domain IV	Domain
C	IPR004540	Translation elongation factor EFG/EF2	Family
C	IPR000795	Translational (tr)-type GTP-binding domain	Domain
C	IPR000640	Elongation factor EFG, domain V-like	Domain
C	IPR031157	Tr-type G domain, conserved site	Conserved Site
C	IPR009022	Elongation factor G, domain III	Domain
C	IPR035647	EF-G domain III/V-like	Homologous Superfamily
C	IPR041095	Elongation Factor G, domain II	Domain
C	IPR004161	Translation elongation factor EFTu-like, domain 2	Domain
C	IPR047872	Elongation factor G, domain IV	Domain
C	IPR009000	Translation protein, beta-barrel domain superfamily	Homologous Superfamily
C	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	Homologous Superfamily
C	IPR005225	Small GTP-binding protein domain	Domain
C	IPR035649	EFG, domain V	Domain
C	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
C	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Homologous Superfamily