2AAR

Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome.

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B [auth R]	d2aarr1	Alpha and beta proteins (a+b)	Ribosomal proteins S24e, L23 and L15e	Ribosomal proteins S24e, L23 and L15e	L23p	Ribosomal protein L23	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
C [auth W]	d2aarw1	All alpha proteins	Long alpha-hairpin	Ribosomal protein L29 (L29p)	Ribosomal protein L29 (L29p)	Ribosomal protein L29 (L29p)	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B [auth R]	SCOP2B Superfamily	Ribosomal proteins S24e L23 and L15e	8038577	3000210	SCOP2B (2022-06-29)
C [auth W]	SCOP2B Superfamily	Ribosomal protein L29 (L29p)	8038586	3000713	SCOP2B (2022-06-29)
D [auth 7]	SCOP2 Family	Trigger factor ribosome-binding domain	8075113	4001241	SCOP2 (2022-06-29)
D [auth 7]	SCOP2 Superfamily	Trigger factor ribosome-binding domain	8075114	3001141	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B [auth R]	Ribosomal_L23_2	e2aarR1	A: a+b two layers	X: Alpha-beta plaits	H: Ribosomal proteins S24e, L23 and L15e (From Topology)	T: Ribosomal proteins S24e, L23 and L15e	F: Ribosomal_L23_2	ECOD (1.6)
C [auth W]	Ribosomal_L29	e2aarW1	A: alpha bundles	X: Long alpha-hairpin	H: Ribosomal protein L29 (L29p) (From Topology)	T: Ribosomal protein L29 (L29p)	F: Ribosomal_L29	ECOD (1.6)
D [auth 7]	Trigger_N	e2aar71	A: a+b two layers	X: Glucose permease domain IIB-like	H: Trigger factor ribosome-binding domain (From Topology)	T: Trigger factor ribosome-binding domain	F: Trigger_N	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B [auth R]	PF00276	Ribosomal protein L23 (Ribosomal_L23)	Ribosomal protein L23	-	Family
C [auth W]	PF00831	Ribosomal L29 protein (Ribosomal_L29)	Ribosomal L29 protein	-	Family
D [auth 7]	PF05697	Bacterial trigger factor protein (TF) (Trigger_N)	Bacterial trigger factor protein (TF)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth 0]	23S ribosomal RNA	-	-	-
B [auth R]	50S ribosomal protein L23	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit non-membrane-bounded organelle
C [auth W]	50S ribosomal protein L29	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit non-membrane-bounded organelle
D [auth 7]	Trigger Factor	isomerase activity catalytic activity, acting on a protein peptidyl-prolyl cis-trans isomerase activity catalytic activity cis-trans isomerase activity RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding ribonucleoprotein complex binding protein-containing complex binding ribosome binding protein folding chaperone	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process 'de novo' cotranslational protein folding organic substance biosynthetic process metabolic process cellular process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process 'de novo' cotranslational protein folding organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process 'de novo' protein folding cell cycle protein unfolding cell division chaperone-mediated protein folding protein localization establishment of protein localization cellular localization nitrogen compound transport transport organic substance transport establishment of localization localization protein transport cellular macromolecule localization macromolecule localization	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B [auth R]	IPR012678	Ribosomal protein uL23/eL15/eS24 core domain superfamily	Homologous Superfamily
B [auth R]	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	Homologous Superfamily
B [auth R]	IPR001014	Large ribosomal subunit protein uL23, conserved site	Conserved Site
B [auth R]	IPR013025	Large ribosomal subunit protein uL23-like	Family
C [auth W]	IPR001854	Large ribosomal subunit protein uL29	Family
C [auth W]	IPR036049	Large ribosomal subunit protein uL29 superfamily	Homologous Superfamily
C [auth W]	IPR018254	Large ribosomal subunit protein uL29, conserved site	Conserved Site
D [auth 7]	IPR046357	Peptidyl-prolyl cis-trans isomerase domain superfamily	Homologous Superfamily
D [auth 7]	IPR036611	Trigger factor ribosome-binding domain superfamily	Homologous Superfamily
D [auth 7]	IPR008881	Trigger factor, ribosome-binding, bacterial	Domain
D [auth 7]	IPR027304	Trigger factor/SurA domain superfamily	Homologous Superfamily
D [auth 7]	IPR037041	Trigger factor, C-terminal domain superfamily	Homologous Superfamily
D [auth 7]	IPR008880	Trigger factor, C-terminal	Domain
D [auth 7]	IPR005215	Trigger factor	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.