2A5S

Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2a5sa1 Alpha and beta proteins (a/b) Periplasmic binding protein-like II Periplasmic binding protein-like II Phosphate binding protein-like N-methyl-D-aspartate receptor subunit 1 Norway rat (Rattus norvegicus ) [TaxId: 10116 ], Norway rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyPhosphate binding protein-like8024224 4000229 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyType 2 solute binding protein-like8036603 3000083 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AF_UNCLASSIFIEDe2a5sA2 A: a/b three-layered sandwichesX: Periplasmic binding protein-like II (From Topology)H: Periplasmic binding protein-like II (From Topology)T: Periplasmic binding protein-like IIF: F_UNCLASSIFIEDECOD (1.6)
APF10613e2a5sA3 A: a/b three-layered sandwichesX: Periplasmic binding protein-like II (From Topology)H: Periplasmic binding protein-like II (From Topology)T: Periplasmic binding protein-like IIF: PF10613ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.190.10 Alpha Beta 3-Layer(aba) Sandwich D-Maltodextrin-Binding Protein domain 2CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00497Bacterial extracellular solute-binding proteins, family 3 (SBP_bac_3)Bacterial extracellular solute-binding proteins, family 3This is a sensor domain found in solute-binding protein family 3 members from Gram-positive bacteria, Gram-negative bacteria and archaea. It can also be found in the N-terminal of the membrane-bound lytic murein transglycosylase F (MltF) protein. Th ...This is a sensor domain found in solute-binding protein family 3 members from Gram-positive bacteria, Gram-negative bacteria and archaea. It can also be found in the N-terminal of the membrane-bound lytic murein transglycosylase F (MltF) protein. This domain recognises Nicotinate, quidalnate, pyridine-2,5-dicarboxylate and salicylate [1].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
N-methyl-D-aspartate receptor NMDAR2A subunit

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR018884Glutamate [NMDA] receptor, epsilon subunit, C-terminalDomain
IPR001638Solute-binding protein family 3/N-terminal domain of MltFDomain
IPR028082Periplasmic binding protein-like IHomologous Superfamily
IPR001828Receptor, ligand binding regionDomain
IPR001320Ionotropic glutamate receptor, C-terminalDomain
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domainDomain
IPR001508Ionotropic glutamate receptor, metazoaFamily
IPR015683Ionotropic glutamate receptorFamily