Annotations: 1ZX5

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1zx5a1	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	Type I phosphomannose isomerase	Putative mannosephosphate isomerase AF0035	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
A	d1zx5a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Type I phosphomannose isomerase	8023973	4002872	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	RmlC-like cupins	8036352	3001825	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PMI_typeI_N	e1zx5A2	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: PMI_typeI_N	ECOD (1.6)
A	Cupin_2_2	e1zx5A3	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: Cupin_2_2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF21621	Mannose-6-phosphate isomerase, cupin domain (MPI_cupin_dom)	Mannose-6-phosphate isomerase, cupin domain	This domain is found in Mannose-6-phosphate isomerase from Archaeoglobus fulgidus (MPI) and similar bacterial sequences. This enzyme catalyses the interconversion of mannose 6-phosphate and fructose 6-phosphate [1,2]. This entry represents the C-term ...	This domain is found in Mannose-6-phosphate isomerase from Archaeoglobus fulgidus (MPI) and similar bacterial sequences. This enzyme catalyses the interconversion of mannose 6-phosphate and fructose 6-phosphate [1,2]. This entry represents the C-terminal domain, which is found associated with PFam:PF20511. This domain shows an all-beta structure.	Domain
A	PF20511	Phosphomannose isomerase type I, catalytic domain (PMI_typeI_cat)	Phosphomannose isomerase type I, catalytic domain	This entry represents the catalytic domain of Phosphomannose isomerase type I enzymes (EC 5.3.1.8) which contains a zinc-binding site. It is composed of beta-strands connected by long loops in a jelly roll conformation [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	mannosephosphate isomerase, putative	isomerase activity intramolecular oxidoreductase activity, interconverting aldoses and ketoses intramolecular oxidoreductase activity mannose-6-phosphate isomerase activity catalytic activity cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding	carbohydrate metabolic process organic substance metabolic process primary metabolic process metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR014628	Mannose-6-phosphate isomerase, Firmicutes type, short form	Family
A	IPR001250	Mannose-6-phosphate isomerase, type I	Family
A	IPR011051	RmlC-like cupin domain superfamily	Homologous Superfamily
A	IPR049071	Mannose-6-phosphate isomerase, cupin domain	Domain
A	IPR046457	Phosphomannose isomerase type I, catalytic domain	Domain
A	IPR014710	RmlC-like jelly roll fold	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.