Annotations: 1ZN1

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C [auth A]	d1zn1a1	Alpha and beta proteins (a+b)	RRF/tRNA synthetase additional domain-like	Ribosome recycling factor, RRF	Ribosome recycling factor, RRF	Ribosome recycling factor, RRF	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C [auth A]	SCOP2B Superfamily	Ribosome recycling factor RRF	8032742	3001524	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C [auth A]	RRF	e1zn1A1	A: a+b two layers	X: RRF/tRNA synthetase additional domain-like	H: Ribosome recycling factor, RRF (From Topology)	T: Ribosome recycling factor, RRF	F: RRF	ECOD (1.6)
D [auth L]	Ribosom_S12_S23	e1zn1L1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: Ribosom_S12_S23	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C [auth A]	PF01765	Ribosome recycling factor (RRF)	Ribosome recycling factor	The ribosome recycling factor (RRF / ribosome release factor) dissociates the ribosome from the mRNA after termination of translation, and is essential bacterial growth [1]. Thus ribosomes are "recycled" and ready for another round of protein synthe ...	The ribosome recycling factor (RRF / ribosome release factor) dissociates the ribosome from the mRNA after termination of translation, and is essential bacterial growth [1]. Thus ribosomes are "recycled" and ready for another round of protein synthesis.	Domain
D [auth L]	PF00164	Ribosomal protein S12/S23 (Ribosom_S12_S23)	Ribosomal protein S12/S23	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B [auth C]	ribosomal 16S RNA	-	-	-
C [auth A]	Ribosome recycling factor	ribonucleoprotein complex binding protein-containing complex binding binding ribosomal large subunit binding ribosome binding	cytoplasmic translational termination cellular biosynthetic process organonitrogen compound biosynthetic process protein-containing complex disassembly cellular component organization organic substance metabolic process organic substance biosynthetic process translational termination cellular component organization or biogenesis protein metabolic process cellular component disassembly organonitrogen compound metabolic process protein-containing complex organization cellular metabolic process cytoplasmic translational termination cellular biosynthetic process organonitrogen compound biosynthetic process protein-containing complex disassembly cellular component organization organic substance metabolic process organic substance biosynthetic process translational termination cellular component organization or biogenesis protein metabolic process cellular component disassembly organonitrogen compound metabolic process protein-containing complex organization cellular metabolic process primary metabolic process translation gene expression macromolecule biosynthetic process biosynthetic process cytoplasmic translation cellular process metabolic process macromolecule metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol
D [auth L]	30S ribosomal protein S12	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding misfolded RNA binding tRNA binding structural molecule activity structural constituent of ribosome	regulation of cellular process cellular biosynthetic process positive regulation of biological process RNA metabolic process positive regulation of cellular metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process regulation of RNA metabolic process organic substance metabolic process positive regulation of biosynthetic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of cellular process cellular biosynthetic process positive regulation of biological process RNA metabolic process positive regulation of cellular metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process regulation of RNA metabolic process organic substance metabolic process positive regulation of biosynthetic process organic substance biosynthetic process positive regulation of macromolecule metabolic process RNA processing regulation of nucleobase-containing compound metabolic process positive regulation of cellular process regulation of biosynthetic process RNA splicing positive regulation of nucleobase-containing compound metabolic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process gene expression regulation of RNA splicing macromolecule biosynthetic process nucleic acid metabolic process positive regulation of RNA metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process positive regulation of gene expression metabolic process cellular process regulation of macromolecule biosynthetic process macromolecule metabolic process positive regulation of RNA splicing regulation of metabolic process positive regulation of cellular biosynthetic process organonitrogen compound metabolic process organonitrogen compound biosynthetic process translation cytoplasmic translation protein metabolic process RNA folding Group I intron splicing RNA splicing, via transesterification reactions with guanosine as nucleophile RNA splicing, via transesterification reactions response to stimulus response to chemical response to antibiotic maintenance of translational fidelity	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit intracellular organelle ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome intracellular anatomical structure cytoplasm cellular anatomical entity cytosol cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit intracellular organelle ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome non-membrane-bounded organelle
A [auth B]	ribosomal 23S RNA	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C [auth A]	IPR023584	Ribosome recycling factor domain	Domain
C [auth A]	IPR036191	RRF superfamily	Homologous Superfamily
C [auth A]	IPR002661	Ribosome recycling factor	Family
D [auth L]	IPR005679	Ribosomal protein uS12, bacterial-type	Family
D [auth L]	IPR006032	Small ribosomal subunit protein uS12	Family
D [auth L]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.