1ZMB

Crystal Structure of the Putative Acetylxylan Esterase from Clostridium acetobutylicum, Northeast Structural Genomics Target CaR6

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1zmba1	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Putative acetylxylan esterase-like	Acetylxylan esterase related enzyme	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
A	d1zmba2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
B	d1zmbb2	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Putative acetylxylan esterase-like	automated matches	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
B	d1zmbb3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
E	d1zmbe2	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Putative acetylxylan esterase-like	automated matches	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
E	d1zmbe3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
C	d1zmbc2	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Putative acetylxylan esterase-like	automated matches	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
C	d1zmbc3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
D	d1zmbd2	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Putative acetylxylan esterase-like	automated matches	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
D	d1zmbd3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
F	d1zmbf2	Alpha and beta proteins (a/b)	Flavodoxin-like	SGNH hydrolase	Putative acetylxylan esterase-like	automated matches	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)
F	d1zmbf3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Clostridium acetobutylicum ATCC 824 ) [TaxId: 272562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Putative acetylxylan esterase-like	8023593	4002509	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	SGNH hydrolase-like	8035973	3001315	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	SGNH hydrolase-like	8035973	3001315	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	SGNH hydrolase-like	8035973	3001315	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	SGNH hydrolase-like	8035973	3001315	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	SGNH hydrolase-like	8035973	3001315	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	SGNH hydrolase-like	8035973	3001315	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	SASA	e1zmbA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: SASA	ECOD (1.6)
B	SASA	e1zmbB1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: SASA	ECOD (1.6)
E	SASA	e1zmbE1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: SASA	ECOD (1.6)
C	SASA	e1zmbC1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: SASA	ECOD (1.6)
D	SASA	e1zmbD1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: SASA	ECOD (1.6)
F	SASA	e1zmbF1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: SASA	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)
A	6.10.170.10	Special	Helix non-globular	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)
B	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)
B	6.10.170.10	Special	Helix non-globular	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)
E	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)
E	6.10.170.10	Special	Helix non-globular	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)
C	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)
C	6.10.170.10	Special	Helix non-globular	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)
D	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)
D	6.10.170.10	Special	Helix non-globular	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)
F	3.40.50.1110	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	SGNH hydrolase	CATH (4.3.0)
F	6.10.170.10	Special	Helix non-globular	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF03629	Carbohydrate esterase, sialic acid-specific acetylesterase (SASA)	Carbohydrate esterase, sialic acid-specific acetylesterase	The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665 [1,2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Acetylxylan esterase related enzyme	hydrolase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR005181	Sialate O-acetylesterase domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR036514	SGNH hydrolase superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.