1Z3H

The exportin Cse1 in its cargo-free, cytoplasmic state

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1z3ha1	All alpha proteins	alpha-alpha superhelix	ARM repeat	Armadillo repeat	Exportin Cse1p	baker's yeast (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)
B	d1z3hb_	All alpha proteins	alpha-alpha superhelix	ARM repeat	Armadillo repeat	Exportin Cse1p	baker's yeast (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Armadillo repeat	8030996	4001272	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	ARM repeat-like	8043375	3000116	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	ARM repeat-like	8043375	3000116	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03378,PF03810,PF08506	e1z3hA1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF03378,PF03810,PF08506	ECOD (1.6)
B	PF03378,PF03810,PF08506	e1z3hB2	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: PF03378,PF03810,PF08506	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF03378	CAS/CSE protein, C-terminus (CAS_CSE1)	CAS/CSE protein, C-terminus	-	Repeat
A, B	PF08506	Cse1 (Cse1)	Cse1	-	Repeat
A, B	PF03810	Importin-beta N-terminal domain (IBN_N)	Importin-beta N-terminal domain	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Importin alpha re-exporter	small GTPase binding protein binding binding enzyme binding GTPase binding nucleocytoplasmic carrier activity nuclear export signal receptor activity molecular carrier activity	cellular process cell cycle protein localization regulation of localization establishment of protein localization cellular localization nitrogen compound transport regulation of cellular process regulation of protein localization nucleocytoplasmic transport transport positive regulation of nucleocytoplasmic transport nuclear transport positive regulation of biological process cellular process cell cycle protein localization regulation of localization establishment of protein localization cellular localization nitrogen compound transport regulation of cellular process regulation of protein localization nucleocytoplasmic transport transport positive regulation of nucleocytoplasmic transport nuclear transport positive regulation of biological process positive regulation of establishment of protein localization positive regulation of protein transport localization cellular macromolecule localization establishment of localization in cell positive regulation of intracellular transport nuclear export regulation of protein export from nucleus positive regulation of cellular process regulation of intracellular transport regulation of biological process regulation of transport organic substance transport biological regulation regulation of establishment of protein localization intracellular transport regulation of nucleocytoplasmic transport regulation of protein transport protein export from nucleus positive regulation of protein export from nucleus establishment of localization positive regulation of transport protein transport regulation of cellular localization macromolecule localization positive regulation of protein localization regulation of intracellular protein transport positive regulation of intracellular protein transport intracellular protein transport cell division RNA import into nucleus RNA transport nucleic acid transport snRNA import into nucleus import into nucleus establishment of RNA localization RNA localization nucleobase-containing compound transport snRNA transport protein localization to nucleus establishment of protein localization to organelle protein localization to organelle protein import into nucleus	membrane-bounded organelle intracellular organelle organelle envelope intracellular anatomical structure organelle nuclear envelope nucleus cellular anatomical entity intracellular membrane-bounded organelle endomembrane system cytoplasm cytosol protein-containing complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR013713	Exportin-2, central domain	Domain
A, B	IPR016024	Armadillo-type fold	Homologous Superfamily
A, B	IPR005043	Exportin-2, C-terminal	Domain
A, B	IPR001494	Importin-beta, N-terminal domain	Domain
A, B	IPR011989	Armadillo-like helical	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.