1YAC

THE 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE YCAC GENE PRODUCT FROM ESCHERICHIA COLI REVEALS AN OCTAMERIC HYDROLASE OF UNKNOWN SPECIFICITY

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1yaca_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	YcaC	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1yacb_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	YcaC	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Isochorismatase-like hydrolases	8031882	4000591	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Isochorismatase-like hydrolases	8044260	3001778	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Isochorismatase-like hydrolases	8044260	3001778	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00857	e1yacA1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: PF00857	ECOD (1.6)
B	PF00857	e1yacB1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: PF00857	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)
B	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00857	Isochorismatase family (Isochorismatase)	Isochorismatase family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	YCAC GENE PRODUCT	hydrolase activity catalytic activity lyase activity identical protein binding protein binding binding	-	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR000868	Isochorismatase-like	Domain
A, B	IPR048239	Probable hydrolase YcaC	Family
A, B	IPR036380	Isochorismatase-like superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.