1XMN
Crystal structure of thrombin bound to heparin
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
D | SCOP2B Superfamily | Trypsin-like serine proteases | 8042154 | 3000114 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | Trypsin-like serine proteases | 8042154 | 3000114 | SCOP2B (2022-06-29) |
H | SCOP2B Superfamily | Trypsin-like serine proteases | 8042154 | 3000114 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Trypsin-like serine proteases | 8042154 | 3000114 | SCOP2B (2022-06-29) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
D | 2.40.10.10 | Mainly Beta | Beta Barrel | Thrombin, subunit H | Trypsin-like serine proteases | CATH (4.3.0) |
F | 2.40.10.10 | Mainly Beta | Beta Barrel | Thrombin, subunit H | Trypsin-like serine proteases | CATH (4.3.0) |
H | 2.40.10.10 | Mainly Beta | Beta Barrel | Thrombin, subunit H | Trypsin-like serine proteases | CATH (4.3.0) |
B | 2.40.10.10 | Mainly Beta | Beta Barrel | Thrombin, subunit H | Trypsin-like serine proteases | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF09396 | Thrombin light chain (Thrombin_light) | Thrombin light chain | Thrombin is an enzyme that cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII. Prothrombin is activated on the surface of a phospholipid membrane where factor Xa removes the activation peptide and cleave ... | Domain | |
PF00089 | Trypsin (Trypsin) | Trypsin | - | Domain |