1XFK

1.8A crystal structure of formiminoglutamase from Vibrio cholerae O1 biovar eltor str. N16961

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1xfka_	Alpha and beta proteins (a/b)	Arginase/deacetylase	Arginase/deacetylase	Arginase-like amidino hydrolases	Formimidoylglutamase HutG	(Vibrio cholerae ) [TaxId: 666 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Arginase-like amidino hydrolases	8031498	4000424	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Arginase/deacetylase-like	8043876	3000260	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00491	e1xfkA1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: Arginase/deacetylase	F: PF00491	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.800.10	Alpha Beta	3-Layer(aba) Sandwich	Arginase	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00491	Arginase family (Arginase)	Arginase family	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Formimidoylglutamase	cation binding manganese ion binding transition metal ion binding ion binding binding metal ion binding small molecule binding formimidoylglutamase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines hydrolase activity catalytic activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds agmatinase activity	catabolic process oxoacid metabolic process amino acid metabolic process organic acid metabolic process histidine catabolic process organic acid catabolic process alpha-amino acid metabolic process glutamine family amino acid metabolic process cellular catabolic process organic substance metabolic process carboxylic acid catabolic process glutamate metabolic process amide catabolic process small molecule metabolic process catabolic process oxoacid metabolic process amino acid metabolic process organic acid metabolic process histidine catabolic process organic acid catabolic process alpha-amino acid metabolic process glutamine family amino acid metabolic process cellular catabolic process organic substance metabolic process carboxylic acid catabolic process glutamate metabolic process amide catabolic process small molecule metabolic process amide metabolic process histidine metabolic process organonitrogen compound catabolic process organonitrogen compound metabolic process cellular metabolic process dicarboxylic acid metabolic process carboxylic acid metabolic process histidine catabolic process to glutamate and formamide primary metabolic process L-amino acid metabolic process proteinogenic amino acid metabolic process metabolic process cellular process small molecule catabolic process formamide metabolic process organic substance catabolic process histidine catabolic process to glutamate and formate monocarboxylic acid metabolic process formate metabolic process organonitrogen compound biosynthetic process arginine metabolic process biogenic amine biosynthetic process putrescine biosynthetic process from arginine, using agmatinase organic substance biosynthetic process putrescine metabolic process polyamine metabolic process putrescine biosynthetic process amine metabolic process biosynthetic process amine biosynthetic process polyamine biosynthetic process putrescine biosynthetic process from arginine biogenic amine metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR005923	Formiminoglutamase	Family
A	IPR020855	Ureohydrolase, manganese-binding site	Binding Site
A	IPR023696	Ureohydrolase domain superfamily	Homologous Superfamily
A	IPR006035	Ureohydrolase	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.