1X57
Solution structures of the HTH domain of human EDF-1 protein
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d1x57a1 | All alpha proteins | lambda repressor-like DNA-binding domains | lambda repressor-like DNA-binding domains | EDF1-like | Endothelial differentiation-related factor 1, EDF1 | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
A | d1x57a3 | Artifacts | Tags | Tags | Tags | C-terminal Tags | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
A | d1x57a2 | Artifacts | Tags | Tags | Tags | N-terminal Tags | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.10.260.40 | Mainly Alpha | Orthogonal Bundle | 434 Repressor (Amino-terminal Domain) | lambda repressor-like DNA-binding domains | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01381 | Helix-turn-helix (HTH_3) | Helix-turn-helix | This large family of DNA binding helix-turn helix proteins includes Cro Swiss:P03036 and CI Swiss:P03034. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be ... | Domain | |
PF08523 | Multiprotein bridging factor 1 (MBF1) | Multiprotein bridging factor 1 | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR001387 | Cro/C1-type helix-turn-helix domain | Domain | |
IPR013729 | Multiprotein bridging factor 1, N-terminal | Domain | |
IPR010982 | Lambda repressor-like, DNA-binding domain superfamily | Homologous Superfamily |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
O60869 | :