1V8P

Crystal structure of PAE2754 from Pyrobaculum aerophilum

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1v8pa_	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
B	d1v8pb1	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
B	d1v8pb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
C	d1v8pc1	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
C	d1v8pc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
D	d1v8pd1	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
D	d1v8pd2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
E	d1v8pe_	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
F	d1v8pf1	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
F	d1v8pf2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
G	d1v8pg1	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
G	d1v8pg2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
H	d1v8ph_	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
I	d1v8pi_	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
J	d1v8pj_	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
K	d1v8pk_	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)
L	d1v8pl_	Alpha and beta proteins (a/b)	PIN domain-like	PIN domain-like	PIN domain	Hypothetical protein PAE2754	(Pyrobaculum aerophilum ) [TaxId: 13773 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	PIN domain	8023253	4000475	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	PIN domain-like	8035633	3001041	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	PIN domain-like	8035633	3001041	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01850	e1v8pA1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
B	PF01850	e1v8pB1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
C	PF01850	e1v8pC1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
D	PF01850	e1v8pD1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
E	PF01850	e1v8pE1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
F	PF01850	e1v8pF1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
G	PF01850	e1v8pG1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
H	PF01850	e1v8pH1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
I	PF01850	e1v8pI1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
J	PF01850	e1v8pJ1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
K	PF01850	e1v8pK1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
L	PF01850	e1v8pL1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
B	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
C	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
D	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
E	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
F	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
G	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
H	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
I	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
J	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
K	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
L	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF01850	PIN domain (PIN)	PIN domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	hypothetical protein PAE2754	nuclease activity hydrolase activity, acting on ester bonds hydrolase activity exonuclease activity catalytic activity cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR002716	PIN domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR029060	PIN-like domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR022907	VapC family	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR044153	Pae0151-like, PIN domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.