1V58

Crystal Structure Of the Reduced Protein Disulfide Bond Isomerase DsbG

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1v58a1	Alpha and beta proteins (a/b)	Thioredoxin fold	Thioredoxin-like	DsbC/DsbG C-terminal domain-like	Thiol:disulfide interchange protein DsbG, C-terminal domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
A	d1v58a2	Alpha and beta proteins (a+b)	Cystatin-like	DsbC/DsbG N-terminal domain-like	DsbC/DsbG N-terminal domain-like	Thiol:disulfide interchange protein DsbG, N-terminal domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1v58b1	Alpha and beta proteins (a/b)	Thioredoxin fold	Thioredoxin-like	DsbC/DsbG C-terminal domain-like	Thiol:disulfide interchange protein DsbG, C-terminal domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1v58b2	Alpha and beta proteins (a+b)	Cystatin-like	DsbC/DsbG N-terminal domain-like	DsbC/DsbG N-terminal domain-like	Thiol:disulfide interchange protein DsbG, N-terminal domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	DsbC/DsbG C-terminal domain-like	8028785	4000486	SCOP2 (2022-06-29)
A	SCOP2 Family	DsbC/DsbG N-terminal domain-like	8028786	4001018	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Thioredoxin-like	8041164	3000031	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	DsbC/DsbG N-terminal domain-like	8041165	3000466	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	DsbC/DsbG N-terminal domain-like	8041165	3000466	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Thioredoxin-like	8041164	3000031	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF10411	e1v58A1	A: a+b two layers	X: Cystatin-like	H: DsbC/DsbG N-terminal domain-like (From Topology)	T: DsbC/DsbG N-terminal domain-like	F: PF10411	ECOD (1.6)
A	PF13098	e1v58A2	A: a+b three layers	X: Thioredoxin-like	H: Thioredoxin-like (From Topology)	T: Thioredoxin-like	F: PF13098	ECOD (1.6)
B	PF10411	e1v58B1	A: a+b two layers	X: Cystatin-like	H: DsbC/DsbG N-terminal domain-like (From Topology)	T: DsbC/DsbG N-terminal domain-like	F: PF10411	ECOD (1.6)
B	PF13098	e1v58B2	A: a+b three layers	X: Thioredoxin-like	H: Thioredoxin-like (From Topology)	T: Thioredoxin-like	F: PF13098	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.450.70	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
A	3.40.30.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaredoxin	Glutaredoxin	CATH (4.3.0)
B	3.10.450.70	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
B	3.40.30.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaredoxin	Glutaredoxin	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF13098	Thioredoxin-like domain (Thioredoxin_2)	Thioredoxin-like domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Thiol:disulfide interchange protein dsbG	isomerase activity intramolecular oxidoreductase activity catalytic activity, acting on a protein intramolecular oxidoreductase activity, transposing S-S bonds catalytic activity protein disulfide isomerase activity identical protein binding protein binding binding protein homodimerization activity protein dimerization activity	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression chaperone-mediated protein folding macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression chaperone-mediated protein folding macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	outer membrane-bounded periplasmic space cell envelope periplasmic space cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR012336	Thioredoxin-like fold	Domain
A, B	IPR033954	Disulphide bond isomerase, DsbC/G	Family
A, B	IPR036249	Thioredoxin-like superfamily	Homologous Superfamily
A, B	IPR009094	Disulphide bond isomerase DsbC/G, N-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.