1ULQ

Crystal structure of tt0182 from Thermus thermophilus HB8

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1ulqa2	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, C-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
A	d1ulqa1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, N-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
B	d1ulqb2	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, C-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
B	d1ulqb1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, N-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
C	d1ulqc2	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, C-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
C	d1ulqc1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, N-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
D	d1ulqd2	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, C-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
D	d1ulqd1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, N-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
E	d1ulqe2	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, C-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
E	d1ulqe1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, N-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
G	d1ulqg2	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, C-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
G	d1ulqg1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, N-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
F	d1ulqf2	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, C-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
F	d1ulqf1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, N-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
H	d1ulqh2	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, C-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
H	d1ulqh1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Thiolase-related	Beta-ketoadipyl CoA thiolase, N-terminal domain	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Thiolase-related	8030485	4000245	SCOP2 (2022-06-29)
A	SCOP2 Family	Thiolase-related	8030487	4000245	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Thiolase-like	8042864	3000122	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Thiolase-like	8042866	3000122	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Thiolase-like	8042864	3000122	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Thiolase-like	8042866	3000122	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Thiolase-like	8042866	3000122	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Thiolase-like	8042864	3000122	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Thiolase-like	8042866	3000122	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Thiolase-like	8042864	3000122	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Thiolase-like	8042866	3000122	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Thiolase-like	8042864	3000122	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Thiolase-like	8042866	3000122	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Thiolase-like	8042864	3000122	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Thiolase-like	8042866	3000122	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Thiolase-like	8042864	3000122	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Thiolase-like	8042864	3000122	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Thiolase-like	8042866	3000122	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Thiolase_C	e1ulqA1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_C	ECOD (1.6)
A	Thiolase_N	e1ulqA2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_N	ECOD (1.6)
B	Thiolase_C	e1ulqB1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_C	ECOD (1.6)
B	Thiolase_N	e1ulqB2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_N	ECOD (1.6)
C	Thiolase_C	e1ulqC1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_C	ECOD (1.6)
C	Thiolase_N	e1ulqC2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_N	ECOD (1.6)
D	Thiolase_C	e1ulqD1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_C	ECOD (1.6)
D	Thiolase_N	e1ulqD2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_N	ECOD (1.6)
E	Thiolase_C	e1ulqE1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_C	ECOD (1.6)
E	Thiolase_N	e1ulqE2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_N	ECOD (1.6)
G	Thiolase_C	e1ulqG1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_C	ECOD (1.6)
G	Thiolase_N	e1ulqG2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_N	ECOD (1.6)
F	Thiolase_C	e1ulqF1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_C	ECOD (1.6)
F	Thiolase_N	e1ulqF2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_N	ECOD (1.6)
H	Thiolase_C	e1ulqH1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_C	ECOD (1.6)
H	Thiolase_N	e1ulqH2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: Thiolase_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
B	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
C	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
D	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
E	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
G	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
F	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
H	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF02803	Thiolase, C-terminal domain (Thiolase_C)	Thiolase, C-terminal domain	Thiolase is reported to be structurally related to beta-ketoacyl synthase (Pfam:PF00109), and also chalcone synthase.	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	PF00108	Thiolase, N-terminal domain (Thiolase_N)	Thiolase, N-terminal domain	Thiolase is reported to be structurally related to beta-ketoacyl synthase (Pfam:PF00109), and also chalcone synthase.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	putative acetyl-CoA acetyltransferase	acyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity catalytic activity	-	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR016039	Thiolase-like	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR020617	Thiolase, C-terminal	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR020616	Thiolase, N-terminal	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR020613	Thiolase, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H	IPR020610	Thiolase, active site	Active Site
A, B, C, D, E A, B, C, D, E, F, G, H	IPR020615	Thiolase, acyl-enzyme intermediate active site	Active Site
A, B, C, D, E A, B, C, D, E, F, G, H	IPR002155	Thiolase	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.