1UB7

The Crystal Analysis of Beta-Keroacyl-[Acyl Carrier Protein] Synthase III (FABH)From Thermus Thermophilus.

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1ub7a1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Chalcone synthase-like	Ketoacyl-ACP synthase III (FabH)	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
B	d1ub7b1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Chalcone synthase-like	Ketoacyl-ACP synthase III (FabH)	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
C	d1ub7c1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Chalcone synthase-like	Ketoacyl-ACP synthase III (FabH)	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
D	d1ub7d1	Alpha and beta proteins (a/b)	Thiolase-like	Thiolase-like	Chalcone synthase-like	Ketoacyl-ACP synthase III (FabH)	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Chalcone synthase-like	8022504	4000864	SCOP2 (2022-06-29)
A	SCOP2 Family	Chalcone synthase-like	8022508	4000864	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Thiolase-like	8034884	3000122	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Thiolase-like	8034888	3000122	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Thiolase-like	8034888	3000122	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Thiolase-like	8034884	3000122	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Thiolase-like	8034888	3000122	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Thiolase-like	8034884	3000122	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Thiolase-like	8034888	3000122	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Thiolase-like	8034884	3000122	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF08541	e1ub7A2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
A	PF08545	e1ub7A3	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08545	ECOD (1.6)
B	PF08541	e1ub7B2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
B	PF08545	e1ub7B3	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08545	ECOD (1.6)
C	PF08541	e1ub7C2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
C	PF08545	e1ub7C3	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08545	ECOD (1.6)
D	PF08541	e1ub7D2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
D	PF08545	e1ub7D3	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08545	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
B	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
C	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)
D	3.40.47.10	Alpha Beta	3-Layer(aba) Sandwich	Peroxisomal Thiolase	Chain A, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF08541	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal (ACP_syn_III_C)	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.	Domain
A, B, C, D	PF08545	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III (ACP_syn_III)	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.180, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	3-oxoacyl-[acyl-carrier protein] synthase	beta-ketoacyl-acyl-carrier-protein synthase III activity acyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity catalytic activity 3-oxoacyl-[acyl-carrier-protein] synthase activity	fatty acid metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process cellular biosynthetic process cellular metabolic process carboxylic acid metabolic process lipid biosynthetic process primary metabolic process organic acid biosynthetic process organic acid metabolic process fatty acid biosynthetic process carboxylic acid biosynthetic process organic substance metabolic process biosynthetic process fatty acid metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process cellular biosynthetic process cellular metabolic process carboxylic acid metabolic process lipid biosynthetic process primary metabolic process organic acid biosynthetic process organic acid metabolic process fatty acid biosynthetic process carboxylic acid biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process cellular lipid metabolic process small molecule metabolic process metabolic process cellular process monocarboxylic acid metabolic process lipid metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR016039	Thiolase-like	Homologous Superfamily
A, B, C, D	IPR004655	Beta-ketoacyl-[acyl-carrier-protein] synthase III	Family
A, B, C, D	IPR013751	Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal	Domain
A, B, C, D	IPR013747	Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal	Domain

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B, C, D	CSO	Parent Component: CYS RESID: AA0205 PSI-MOD : L-cysteine sulfenic acid MOD:00210

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.