Annotations: 1TR8

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01849	e1tr8A5	A: beta sandwiches	X: Nascent polypeptide-associated complex (NAC) dimerization domain (From Topology)	H: Nascent polypeptide-associated complex (NAC) dimerization domain (From Topology)	T: Nascent polypeptide-associated complex (NAC) dimerization domain	F: PF01849	ECOD (1.6)
A	PF19026	e1tr8A6	A: alpha arrays	X: RuvA-C	H: RuvA-C, UBA, CRAL/TRIO-N, HBS1 (From Topology)	T: RuvA-C, UBA, CRAL/TRIO-N, HBS1	F: PF19026	ECOD (1.6)
B	PF01849	e1tr8B5	A: beta sandwiches	X: Nascent polypeptide-associated complex (NAC) dimerization domain (From Topology)	H: Nascent polypeptide-associated complex (NAC) dimerization domain (From Topology)	T: Nascent polypeptide-associated complex (NAC) dimerization domain	F: PF01849	ECOD (1.6)
B	PF19026	e1tr8B6	A: alpha arrays	X: RuvA-C	H: RuvA-C, UBA, CRAL/TRIO-N, HBS1 (From Topology)	T: RuvA-C, UBA, CRAL/TRIO-N, HBS1	F: PF19026	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.20.70.30	Mainly Beta	Single Sheet	Ubiquitin Ligase Nedd4	Chain: W	CATH (4.3.0)
A	1.10.8.10	Mainly Alpha	Orthogonal Bundle	Helicase, Ruva Protein	domain 3	CATH (4.3.0)
B	2.20.70.30	Mainly Beta	Single Sheet	Ubiquitin Ligase Nedd4	Chain: W	CATH (4.3.0)
B	1.10.8.10	Mainly Alpha	Orthogonal Bundle	Helicase, Ruva Protein	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF19026	HYPK UBA domain (HYPK_UBA)	HYPK UBA domain	This entry represents the UBA domain [1] found at the C-terminus of the HYPK protein and its homologues. This domain in HYPK mediates a protein interaction with the Naa15 C-terminus [1].	Domain
A, B	PF01849	NAC domain (NAC)	NAC domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	conserved protein (MTH177)	RNA binding binding organic cyclic compound binding nucleic acid binding	protein localization establishment of protein localization cellular localization nitrogen compound transport transport organic substance transport establishment of localization localization protein transport cellular macromolecule localization macromolecule localization cellular process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR005231	Nascent polypeptide-associated complex (NAC), archaeal	Family
A, B	IPR038187	NAC A/B domain superfamily	Homologous Superfamily
A, B	IPR044034	Nascent polypeptide-associated complex subunit alpha-like, UBA domain	Domain
A, B	IPR009060	UBA-like superfamily	Homologous Superfamily
A, B	IPR002715	Nascent polypeptide-associated complex NAC domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.