1TE1

Crystal structure of family 11 xylanase in complex with inhibitor (XIP-I)

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1te1a_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	(Trans)glycosidases	Type II chitinase	Xylanase inhibitor protein I, XIP-I	(Triticum aestivum ) [TaxId: 4565 ],	SCOPe (2.08)
B	d1te1b_	All beta proteins	Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	Xylanase/endoglucanase 11/12	Xylanase II	(Talaromyces funiculosus ) [TaxId: 28572 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	(Trans)glycosidases	8040112	3000313	SCOP2B (2022-06-29)
B	SCOP2 Family	Xylanase/endoglucanase 11/12	8027756	4002742	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Concanavalin A-like lectins/glucanases	8040135	3000120	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00704	e1te1A1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: PF00704	ECOD (1.6)
B	PF00457	e1te1B1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Concanavalin A-like lectins/glucanases	F: PF00457	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.20.20.80	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glycosidases	CATH (4.3.0)
B	2.60.120.180	Mainly Beta	Sandwich	Jelly Rolls	Glycoside hydrolase family 11/12, catalytic domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00704	Glycosyl hydrolases family 18 (Glyco_hydro_18)	Glycosyl hydrolases family 18	-	Domain
B	PF00457	Glycosyl hydrolases family 11 (Glyco_hydro_11)	Glycosyl hydrolases family 11	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	xylanase inhibitor protein I	enzyme regulator activity molecular function inhibitor activity molecular function regulator activity enzyme inhibitor activity chitinase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity	carbohydrate metabolic process organic substance metabolic process primary metabolic process metabolic process biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response response to external stimulus response to biotic stimulus defense response to fungus defense response to other organism response to stress response to external biotic stimulus carbohydrate metabolic process organic substance metabolic process primary metabolic process metabolic process biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response response to external stimulus response to biotic stimulus defense response to fungus defense response to other organism response to stress response to external biotic stimulus response to fungus	extracellular region cellular anatomical entity
B	endo-1,4-xylanase	xylanase activity hydrolase activity, acting on glycosyl bonds endo-1,4-beta-xylanase activity hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity	carbohydrate metabolic process xylan catabolic process catabolic process hemicellulose metabolic process cell wall organization or biogenesis carbohydrate catabolic process hemicellulose catabolic process primary metabolic process macromolecule catabolic process cell wall macromolecule catabolic process xylan metabolic process polysaccharide metabolic process organic substance metabolic process polysaccharide catabolic process carbohydrate metabolic process xylan catabolic process catabolic process hemicellulose metabolic process cell wall organization or biogenesis carbohydrate catabolic process hemicellulose catabolic process primary metabolic process macromolecule catabolic process cell wall macromolecule catabolic process xylan metabolic process polysaccharide metabolic process organic substance metabolic process polysaccharide catabolic process metabolic process cellular process macromolecule metabolic process cell wall polysaccharide metabolic process organic substance catabolic process cell wall macromolecule metabolic process cell wall polysaccharide catabolic process	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A	IPR045321	Chitinase Cts1-like	Domain
A	IPR001223	Glycoside hydrolase family 18, catalytic domain	Domain
B	IPR001137	Glycoside hydrolase family 11	Family
B	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	Homologous Superfamily
B	IPR018208	Glycoside hydrolase family 11, active site 1	Active Site
B	IPR013319	Glycoside hydrolase family 11/12	Homologous Superfamily
B	IPR033123	Glycosyl hydrolases family 11 (GH11) domain	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.