Annotations: 1SZN

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1szna1	All beta proteins	Glycosyl hydrolase domain	Glycosyl hydrolase domain	alpha-Amylases, C-terminal beta-sheet domain	Melibiase	(Trichoderma reesei ) [TaxId: 51453 ],	SCOPe (2.08)
A	d1szna2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	(Trans)glycosidases	Amylase, catalytic domain	Melibiase	(Trichoderma reesei ) [TaxId: 51453 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	alpha-Amylases C-terminal beta-sheet domain	8027462	4002636	SCOP2 (2022-06-29)
A	SCOP2 Family	Amylase catalytic domain	8027464	4003138	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Glycosyl hydrolase domain-like	8039841	3001528	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	(Trans)glycosidases	8039843	3000313	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PLN02229	e1sznA1	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycosyl hydrolase domain (From Topology)	T: Glycosyl hydrolase domain	F: PLN02229	ECOD (1.6)
A	Glyco_hydro_31_N	e1sznA2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_31_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
A	2.60.40.1180	Mainly Beta	Sandwich	Immunoglobulin-like	Golgi alpha-mannosidase II	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF16499	Alpha galactosidase A (Melibiase_2)	Alpha galactosidase A	-	Family
A	PF17801	Alpha galactosidase C-terminal beta sandwich domain (Melibiase_C)	Alpha galactosidase C-terminal beta sandwich domain	This domain is found at the C-terminus of alpha galactosidase enzymes.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	alpha-galactosidase	alpha-galactosidase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity galactosidase activity	carbohydrate metabolic process organic substance metabolic process primary metabolic process metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR000111	Glycoside hydrolase family 27/36, conserved site	Conserved Site
A	IPR002241	Glycoside hydrolase, family 27	Family
A	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A	IPR013785	Aldolase-type TIM barrel	Homologous Superfamily
A	IPR041233	Alpha galactosidase, C-terminal beta sandwich domain	Domain
A	IPR013780	Glycosyl hydrolase, all-beta	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.