Annotations: 1SJP

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1sjpa1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
A	d1sjpa2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
A	d1sjpa3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
B	d1sjpb1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
B	d1sjpb2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)
B	d1sjpb3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Mycobacterium tuberculosis ) [TaxId: 1773 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	GroEL chaperone ATPase domain	8029964	4001469	SCOP2 (2022-06-29)
A	SCOP2 Family	GroEL-like chaperone apical domain	8029966	4003504	SCOP2 (2022-06-29)
A	SCOP2 Family	GroEL-like chaperone intermediate domain	8029967	4001214	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	GroEL equatorial domain-like	8042343	3001651	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	GroEL apical domain-like	8042345	3000963	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	GroEL-intermediate domain like	8042346	3001087	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	GroEL-intermediate domain like	8042346	3001087	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL equatorial domain-like	8042343	3001651	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL equatorial domain-like	8042343	3001651	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL apical domain-like	8042345	3000963	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL-intermediate domain like	8042346	3001087	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00118	e1sjpA2	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
A	PF00118	e1sjpA1	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
A	F_UNCLASSIFIED	e1sjpA3	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF00118	e1sjpB1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: PF00118	ECOD (1.6)
B	PF00118	e1sjpB3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00118	ECOD (1.6)
B	F_UNCLASSIFIED	e1sjpB2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: F_UNCLASSIFIED	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
A	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
A	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
B	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
B	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
B	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	60 kDa chaperonin 2	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding isomerase activity catalytic activity ATP-dependent protein folding chaperone protein folding chaperone ATP-dependent activity	protein refolding organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein refolding organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process biological process involved in interspecies interaction between organisms adhesion of symbiont to host biological process involved in interaction with host biological process involved in symbiotic interaction chaperone cofactor-dependent protein refolding chaperone-mediated protein folding 'de novo' protein folding 'de novo' post-translational protein folding response to decreased oxygen levels response to stimulus response to hypoxia response to stress response to oxygen levels response to abiotic stimulus regulation of molecular function positive regulation of molecular function regulation of DNA binding regulation of binding positive regulation of transcription regulatory region DNA binding regulation of transcription regulatory region DNA binding biological regulation positive regulation of binding positive regulation of DNA binding response to heat response to temperature stimulus	cell periphery external encapsulating structure glycocalyx cellular anatomical entity capsule extracellular region protein-containing complex chaperonin ATPase complex intracellular anatomical structure protein folding chaperone complex GroEL-GroES complex cytoplasm cytosol intracellular protein-containing complex cell periphery external encapsulating structure glycocalyx cellular anatomical entity capsule extracellular region protein-containing complex chaperonin ATPase complex intracellular anatomical structure protein folding chaperone complex GroEL-GroES complex cytoplasm cytosol intracellular protein-containing complex host intracellular membrane-bounded organelle host cellular component host intracellular part host cell cytoplasm host cell part host intracellular region host cell mitochondrion host cell cytoplasm part host intracellular organelle cell surface plasma membrane membrane cell wall peptidoglycan-based cell wall

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
A, B	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
A, B	IPR001844	Chaperonin Cpn60/GroEL	Family
A, B	IPR018370	Chaperonin Cpn60, conserved site	Conserved Site
A, B	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
A, B	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.