1S7O

Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d1s7ob_	All alpha proteins	DNA/RNA-binding 3-helical bundle	Sigma3 and sigma4 domains of RNA polymerase sigma factors	YlxM/p13-like	Hypothetical protein SPy1201	(Streptococcus pyogenes serotype M3 ) [TaxId: 301448 ],	SCOPe (2.08)
A	d1s7oa_	All alpha proteins	DNA/RNA-binding 3-helical bundle	Sigma3 and sigma4 domains of RNA polymerase sigma factors	YlxM/p13-like	Hypothetical protein SPy1201	(Streptococcus pyogenes serotype M3 ) [TaxId: 301448 ],	SCOPe (2.08)
C	d1s7oc_	All alpha proteins	DNA/RNA-binding 3-helical bundle	Sigma3 and sigma4 domains of RNA polymerase sigma factors	YlxM/p13-like	Hypothetical protein SPy1201	(Streptococcus pyogenes serotype M3 ) [TaxId: 301448 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Sigma factor domain-like	8039264	3000953	SCOP2B (2022-06-29)
A	SCOP2 Family	YlxM/p13-like	8026885	4002303	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Sigma factor domain-like	8039264	3000953	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	Sigma factor domain-like	8039264	3000953	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PF04297	e1s7oB1	A: alpha arrays	X: HTH	H: HTH	T: tri-helical	F: PF04297	ECOD (1.6)
A	PF04297	e1s7oA1	A: alpha arrays	X: HTH	H: HTH	T: tri-helical	F: PF04297	ECOD (1.6)
C	PF04297	e1s7oC1	A: alpha arrays	X: HTH	H: HTH	T: tri-helical	F: PF04297	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	1.10.10.10	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	CATH (4.3.0)
A	1.10.10.10	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	CATH (4.3.0)
C	1.10.10.10	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF04297	Putative helix-turn-helix protein, YlxM / p13 like (UPF0122)	Putative helix-turn-helix protein, YlxM / p13 like	-	Family

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR013324	RNA polymerase sigma factor, region 3/4-like	Homologous Superfamily
A, B, C	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
A, B, C	IPR007394	Putative helix-turn-helix protein, YlxM/p13-like	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.