1S3Q

Crystal structures of a novel open pore ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1s3qa1	All alpha proteins	Ferritin-like	Ferritin-like	Ferritin	Non-hem ferritin	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
B	d1s3qb_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
C	d1s3qc_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
D	d1s3qd_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
E	d1s3qe_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
F	d1s3qf_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
G	d1s3qg_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
H	d1s3qh_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
I	d1s3qi_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
J	d1s3qj_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
K	d1s3qk_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
L	d1s3ql_	All alpha proteins	Ferritin-like	Ferritin-like	automated matches	automated matches	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Ferritin	8019959	4000839	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Ferritin-like	8032339	3001658	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Ferritin-like	8032339	3001658	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Ferritin	e1s3qA1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
B	Ferritin	e1s3qB1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
C	Ferritin	e1s3qC1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
D	Ferritin	e1s3qD1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
E	Ferritin	e1s3qE1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
F	Ferritin	e1s3qF1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
G	Ferritin	e1s3qG1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
H	Ferritin	e1s3qH1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
I	Ferritin	e1s3qI1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
J	Ferritin	e1s3qJ1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
K	Ferritin	e1s3qK1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)
L	Ferritin	e1s3qL1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Ferritin	F: Ferritin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
B	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
C	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
D	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
E	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
F	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
G	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
H	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
I	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
J	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
K	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)
L	1.20.1260.10	Mainly Alpha	Up-down Bundle	Ferritin	Ferritin, core subunit, four-helix bundle	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF00210	Ferritin-like domain (Ferritin)	Ferritin-like domain	This family contains ferritins and other ferritin-like proteins such as members of the DPS family and bacterioferritins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	ferritin	cation binding ferric iron binding transition metal ion binding iron ion binding ion binding binding metal ion binding small molecule binding identical protein binding protein binding	intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis localization transport iron ion transport transition metal ion transport intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis localization transport iron ion transport transition metal ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR009040	Ferritin-like diiron domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR041719	Ferritin, prokaryotic-type	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR012347	Ferritin-like	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR009078	Ferritin-like superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR001519	Ferritin	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR008331	Ferritin/DPS protein domain	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.