Annotations: 1S3P

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1s3pa_	All alpha proteins	EF Hand-like	EF-hand	Parvalbumin	Parvalbumin	Norway rat (Rattus norvegicus ) [TaxId: 10116 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	EF-hand	8040963	3001983	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	EF-hand_7_3	e1s3pA1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: EF-hand_7_3	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.238.10	Mainly Alpha	Orthogonal Bundle	Recoverin	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF13499	EF-hand domain pair (EF-hand_7)	EF-hand domain pair	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Parvalbumin alpha	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding protein-containing complex binding identical protein binding protein binding	developmental process ear development sensory organ development inner ear development cochlea development animal organ development anatomical structure development trans-synaptic signaling regulation of biological process signaling biological regulation cell-cell signaling chemical synaptic transmission cell communication developmental process ear development sensory organ development inner ear development cochlea development animal organ development anatomical structure development trans-synaptic signaling regulation of biological process signaling biological regulation cell-cell signaling chemical synaptic transmission cell communication synaptic signaling anterograde trans-synaptic signaling cellular process inhibitory chemical synaptic transmission organic substance metabolic process biosynthetic process cellular biosynthetic process cellular metabolic process organic substance biosynthetic process metabolic process macromolecule metabolic process gene expression macromolecule biosynthetic process excitatory chemical synaptic transmission	axon synapse neuron projection cellular anatomical entity axon terminus plasma membrane bounded cell projection presynapse cell projection distal axon terminal bouton cell junction neuron projection terminus somatodendritic compartment cell body axon synapse neuron projection cellular anatomical entity axon terminus plasma membrane bounded cell projection presynapse cell projection distal axon terminal bouton cell junction neuron projection terminus somatodendritic compartment cell body neuronal cell body intracellular anatomical structure cytoplasm stereocilium actin-based cell projection organelle stereocilium bundle cluster of actin-based cell projections protein-containing complex cell cortex cuticular plate cortical cytoskeleton actin cytoskeleton intracellular organelle cell periphery cytoskeleton intracellular non-membrane-bounded organelle cortical actin cytoskeleton non-membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR008080	Parvalbumin	Family
A	IPR018247	EF-Hand 1, calcium-binding site	Binding Site
A	IPR002048	EF-hand domain	Domain
A	IPR011992	EF-hand domain pair	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.