Annotations: 1RQ0

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1rq0a_	Multi-domain proteins (alpha and beta)	Release factor	Release factor	Release factor	Peptide chain release factor 1, RF1	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
B	d1rq0b_	Multi-domain proteins (alpha and beta)	Release factor	Release factor	Release factor	Peptide chain release factor 1, RF1	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
C	d1rq0c_	Multi-domain proteins (alpha and beta)	Release factor	Release factor	Release factor	Peptide chain release factor 1, RF1	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Peptidyl-tRNA hydrolase domain	8054403	4002570	SCOP2 (2022-06-29)
A	SCOP2 Family	PCRF domain-like	8026496	4002864	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Peptidyl-tRNA hydrolase domain-like	8054404	3001421	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	RNA-binding domain RBD	8054402	3000110	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Release factor N-terminal domain-like	8038875	3001827	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	RNA-binding domain RBD	8054402	3000110	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Peptidyl-tRNA hydrolase domain-like	8054404	3001421	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Release factor N-terminal domain-like	8038875	3001827	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Release factor N-terminal domain-like	8038875	3001827	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	RNA-binding domain RBD	8054402	3000110	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Peptidyl-tRNA hydrolase domain-like	8054404	3001421	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e1rq0A1	A: alpha bundles	X: Release factor (Pfam 00472) N-terminal alpha helical domain (From Topology)	H: Release factor (Pfam 00472) N-terminal alpha helical domain (From Topology)	T: Release factor (Pfam 00472) N-terminal alpha helical domain	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF03462	e1rq0A2	A: a+b two layers	X: Alpha-beta plaits	H: Ferredoxin-like domain in release factor (From Topology)	T: Ferredoxin-like domain in release factor	F: PF03462	ECOD (1.6)
A	F_UNCLASSIFIED	e1rq0A4	A: a+b two layers	X: dsRBD-like	H: Peptidyl-tRNA hydrolase domain-like (From Topology)	T: Peptidyl-tRNA hydrolase domain-like	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF00472	e1rq0A3	A: a+b two layers	X: dsRBD-like	H: Peptidyl-tRNA hydrolase domain-like (From Topology)	T: Peptidyl-tRNA hydrolase domain-like	F: PF00472	ECOD (1.6)
B	F_UNCLASSIFIED	e1rq0B1	A: alpha bundles	X: Release factor (Pfam 00472) N-terminal alpha helical domain (From Topology)	H: Release factor (Pfam 00472) N-terminal alpha helical domain (From Topology)	T: Release factor (Pfam 00472) N-terminal alpha helical domain	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF03462	e1rq0B2	A: a+b two layers	X: Alpha-beta plaits	H: Ferredoxin-like domain in release factor (From Topology)	T: Ferredoxin-like domain in release factor	F: PF03462	ECOD (1.6)
B	PF00472	e1rq0B3	A: a+b two layers	X: dsRBD-like	H: Peptidyl-tRNA hydrolase domain-like (From Topology)	T: Peptidyl-tRNA hydrolase domain-like	F: PF00472	ECOD (1.6)
C	F_UNCLASSIFIED	e1rq0C1	A: alpha bundles	X: Release factor (Pfam 00472) N-terminal alpha helical domain (From Topology)	H: Release factor (Pfam 00472) N-terminal alpha helical domain (From Topology)	T: Release factor (Pfam 00472) N-terminal alpha helical domain	F: F_UNCLASSIFIED	ECOD (1.6)
C	PF03462	e1rq0C2	A: a+b two layers	X: Alpha-beta plaits	H: Ferredoxin-like domain in release factor (From Topology)	T: Ferredoxin-like domain in release factor	F: PF03462	ECOD (1.6)
C	PF00472	e1rq0C3	A: a+b two layers	X: dsRBD-like	H: Peptidyl-tRNA hydrolase domain-like (From Topology)	T: Peptidyl-tRNA hydrolase domain-like	F: PF00472	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	6.10.140.160	Special	Helix non-globular	Helix Hairpins		CATH (4.3.0)
A	3.30.70.1660	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
A	3.30.160.20	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain		CATH (4.3.0)
B	6.10.140.160	Special	Helix non-globular	Helix Hairpins		CATH (4.3.0)
B	3.30.70.1660	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
B	3.30.160.20	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain		CATH (4.3.0)
C	6.10.140.160	Special	Helix non-globular	Helix Hairpins		CATH (4.3.0)
C	3.30.70.1660	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits		CATH (4.3.0)
C	3.30.160.20	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF03462	PCRF domain (PCRF)	PCRF domain	This domain is found in peptide chain release factors.	Domain
A, B, C	PF00472	RF-1 domain (RF-1)	RF-1 domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	Peptide chain release factor 1	translation release factor activity, codon specific translation regulator activity binding organic cyclic compound binding translation regulator activity, nucleic acid binding translation release factor activity nucleic acid binding translation termination factor activity translation factor activity, RNA binding	-	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR004373	Peptide chain release factor 1	Family
A, B, C	IPR000352	Peptide chain release factor class I	Domain
A, B, C	IPR045853	Peptide chain release factor class I superfamily	Homologous Superfamily
A, B, C	IPR005139	Peptide chain release factor	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.