Annotations: 1RP0

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1rp0a1	Alpha and beta proteins (a/b)	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	Thi4-like	Thiazole biosynthetic enzyme Thi4	thale cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
B	d1rp0b_	Alpha and beta proteins (a/b)	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	Thi4-like	Thiazole biosynthetic enzyme Thi4	thale cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Thi4-like	8001242	4000050	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Thi4/GidA-like	8001243	3000051	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Thi4/GidA-like	8001243	3000051	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01946	e1rp0A1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: PF01946	ECOD (1.6)
B	PF01946	e1rp0B1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: PF01946	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	6.10.250.160	Special	Helix non-globular	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
A	3.50.50.60	Alpha Beta	3-Layer(bba) Sandwich	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	CATH (4.3.0)
B	6.10.250.160	Special	Helix non-globular	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
B	3.50.50.60	Alpha Beta	3-Layer(bba) Sandwich	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01946	Thi4 family (Thi4)	Thi4 family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Thiazole biosynthetic enzyme	protein binding binding protein domain specific binding identical protein binding protein homodimerization activity protein dimerization activity cation binding transition metal ion binding iron ion binding ion binding metal ion binding small molecule binding zinc ion binding pentosyltransferase activity protein binding binding protein domain specific binding identical protein binding protein homodimerization activity protein dimerization activity cation binding transition metal ion binding iron ion binding ion binding metal ion binding small molecule binding zinc ion binding pentosyltransferase activity glycosyltransferase activity transferase activity catalytic activity	cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process oxazole or thiazole biosynthetic process oxazole or thiazole metabolic process metabolic process response to abiotic stimulus response to cold response to temperature stimulus organonitrogen compound metabolic process cellular biosynthetic process cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process oxazole or thiazole biosynthetic process oxazole or thiazole metabolic process metabolic process response to abiotic stimulus response to cold response to temperature stimulus organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process thiazole metabolic process organic cyclic compound metabolic process sulfur compound biosynthetic process organic substance metabolic process biosynthetic process thiazole biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process sulfur compound metabolic process organic hydroxy compound metabolic process thiamine-containing compound metabolic process vitamin biosynthetic process alcohol metabolic process thiamine metabolic process thiamine biosynthetic process small molecule metabolic process pyrimidine-containing compound biosynthetic process primary alcohol biosynthetic process water-soluble vitamin metabolic process pyrimidine-containing compound metabolic process water-soluble vitamin biosynthetic process small molecule biosynthetic process vitamin metabolic process organic hydroxy compound biosynthetic process alcohol biosynthetic process thiamine-containing compound biosynthetic process primary alcohol metabolic process	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle plastid plastid stroma chloroplast stroma chloroplast cytosol cell periphery membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle plastid plastid stroma chloroplast stroma chloroplast cytosol cell periphery plasma membrane membrane stromule organelle envelope plastid envelope chloroplast envelope intracellular non-membrane-bounded organelle thylakoid non-membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR027495	Thiamine thiazole synthase	Family
A, B	IPR036188	FAD/NAD(P)-binding domain superfamily	Homologous Superfamily
A, B	IPR002922	Thiazole biosynthetic enzyme Thi4 family	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.