Annotations: 1R6K

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1r6ka_	All beta proteins	E2 regulatory, transactivation domain	E2 regulatory, transactivation domain	E2 regulatory, transactivation domain	E2 regulatory, transactivation domain	(human papillomavirus 11 ) [TaxId: 10580 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	E2 regulatory transactivation domain	8040404	3002015	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00508	e1r6kA3	A: beta sandwiches	X: E2 regulatory, transactivation domain (From Topology)	H: E2 regulatory, transactivation domain (From Topology)	T: E2 regulatory, transactivation domain	F: PF00508	ECOD (1.6)
A	PF00508	e1r6kA2	A: alpha bundles	X: Alpha-helical subdomain in E2 regularoty transactivation domain (From Topology)	H: Alpha-helical subdomain in E2 regularoty transactivation domain (From Topology)	T: Alpha-helical subdomain in E2 regularoty transactivation domain	F: PF00508	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.287.30	Mainly Alpha	Orthogonal Bundle	Helix Hairpins	E2 (early) protein, N terminal domain, subdomain 1	CATH (4.3.0)
A	2.170.200.10	Mainly Beta	Beta Complex	Regulatory Protein E2	Chain: A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00508	E2 (early) protein, N terminal (PPV_E2_N)	E2 (early) protein, N terminal	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	HPV11 REGULATORY PROTEIN E2	DNA binding binding organic cyclic compound binding nucleic acid binding nucleoside phosphate binding nucleotide binding heterocyclic compound binding small molecule binding transcription regulator activity DNA-binding transcription factor activity	nucleobase-containing compound metabolic process organic cyclic compound metabolic process DNA replication organic substance metabolic process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process cellular biosynthetic process cellular metabolic process viral DNA genome replication viral life cycle nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process DNA replication organic substance metabolic process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process cellular biosynthetic process cellular metabolic process viral DNA genome replication viral life cycle nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid biosynthetic process biosynthetic process viral genome replication organic cyclic compound biosynthetic process organic substance biosynthetic process viral process cellular process DNA biosynthetic process regulation of biological process biological regulation regulation of macromolecule metabolic process regulation of primary metabolic process regulation of nucleobase-containing compound metabolic process regulation of metabolic process regulation of DNA replication regulation of DNA metabolic process RNA metabolic process gene expression RNA biosynthetic process DNA-templated transcription	host intracellular membrane-bounded organelle host cellular component host intracellular part host cell part host intracellular region cellular anatomical entity host cell nucleus host intracellular organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR033668	Regulatory protein E2	Family
A	IPR042503	E2 regulatory, transactivation domain, subdomain 1	Homologous Superfamily
A	IPR001866	Papillomavirus E2, N-terminal	Domain
A	IPR036050	E2 regulatory, transactivation domain	Homologous Superfamily
A	IPR042504	E2 regulatory, transactivation domain, subdomain 2	Homologous Superfamily
A	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	Homologous Superfamily
A	IPR000427	Papillomavirus E2, C-terminal	Domain
A	IPR035975	E2/EBNA1, C-terminal	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.