1Q3G

MurA (Asp305Ala) liganded with tetrahedral reaction intermediate

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1q3ga_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
B	d1q3gb_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
C	d1q3gc_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
D	d1q3gd_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
E	d1q3ge_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
I	d1q3gi_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
J	d1q3gj_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
K	d1q3gk_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
L	d1q3gl_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
N [auth X]	d1q3gx_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
O [auth Y]	d1q3gy_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
F	d1q3gf_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
G	d1q3gg_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
H	d1q3gh_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
M [auth W]	d1q3gw_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)
P [auth Z]	d1q3gz_	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)	(Enterobacter cloacae ) [TaxId: 550 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
N [auth X]	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
O [auth Y]	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
M [auth W]	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)
P [auth Z]	SCOP2B Superfamily	EPT/RTPC-like	8035769	3001530	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	EPSP_synthase_C_1	e1q3gA1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
A	EPSP_synthase_N	e1q3gA2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
B	EPSP_synthase_C_1	e1q3gB1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
B	EPSP_synthase_N	e1q3gB2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
C	EPSP_synthase_C_1	e1q3gC1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
C	EPSP_synthase_N	e1q3gC2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
D	EPSP_synthase_C_1	e1q3gD2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
D	EPSP_synthase_N	e1q3gD1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
E	EPSP_synthase_C_1	e1q3gE1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
E	EPSP_synthase_N	e1q3gE2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
I	EPSP_synthase_C_1	e1q3gI2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
I	EPSP_synthase_N	e1q3gI1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
J	EPSP_synthase_C_1	e1q3gJ2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
J	EPSP_synthase_N	e1q3gJ1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
K	EPSP_synthase_C_1	e1q3gK2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
K	EPSP_synthase_N	e1q3gK1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
L	EPSP_synthase_C_1	e1q3gL1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
L	EPSP_synthase_N	e1q3gL2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
N [auth X]	EPSP_synthase_C_1	e1q3gX2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
N [auth X]	EPSP_synthase_N	e1q3gX1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
O [auth Y]	EPSP_synthase_C_1	e1q3gY1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
O [auth Y]	EPSP_synthase_N	e1q3gY2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
F	EPSP_synthase_C_1	e1q3gF2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
F	EPSP_synthase_N	e1q3gF1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
G	EPSP_synthase_C_1	e1q3gG2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
G	EPSP_synthase_N	e1q3gG1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
H	EPSP_synthase_C_1	e1q3gH1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
H	EPSP_synthase_N	e1q3gH2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
M [auth W]	EPSP_synthase_C_1	e1q3gW1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
M [auth W]	EPSP_synthase_N	e1q3gW2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)
P [auth Z]	EPSP_synthase_C_1	e1q3gZ1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_C_1	ECOD (1.6)
P [auth Z]	EPSP_synthase_N	e1q3gZ2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: EPSP_synthase_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
B	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
C	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
D	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
E	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
I	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
J	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
K	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
L	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
N [auth X]	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
O [auth Y]	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
F	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
G	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
H	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
M [auth W]	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
P [auth Z]	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M [auth W], N [auth X], O [auth Y], P [auth Z]	PF00275	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) (EPSP_synthase)	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M [auth W], N [auth X], O [auth Y], P [auth Z]	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity transferase activity transferase activity, transferring alkyl or aryl (other than methyl) groups catalytic activity	developmental process regulation of biological process regulation of developmental process biological regulation regulation of cell shape cell morphogenesis regulation of cell morphogenesis anatomical structure morphogenesis anatomical structure development regulation of biological quality regulation of anatomical structure morphogenesis cellular process cell cycle cellular biosynthetic process developmental process regulation of biological process regulation of developmental process biological regulation regulation of cell shape cell morphogenesis regulation of cell morphogenesis anatomical structure morphogenesis anatomical structure development regulation of biological quality regulation of anatomical structure morphogenesis cellular process cell cycle cellular biosynthetic process cell wall organization or biogenesis glycosaminoglycan metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process cellular component biogenesis organic substance metabolic process peptidoglycan metabolic process organic substance biosynthetic process glycosaminoglycan biosynthetic process cellular component organization or biogenesis carbohydrate derivative biosynthetic process peptidoglycan-based cell wall biogenesis organonitrogen compound metabolic process cellular metabolic process macromolecule biosynthetic process peptidoglycan biosynthetic process cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process aminoglycan metabolic process aminoglycan biosynthetic process metabolic process macromolecule metabolic process amino sugar biosynthetic process nucleotide-sugar metabolic process primary metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process UDP-N-acetylgalactosamine biosynthetic process UDP-N-acetylgalactosamine metabolic process nucleobase-containing small molecule metabolic process organic cyclic compound biosynthetic process amino sugar metabolic process small molecule metabolic process phosphorus metabolic process nucleotide-sugar biosynthetic process cell division cellular component organization cell wall organization external encapsulating structure organization	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M [auth W], N [auth X], O [auth Y], P [auth Z]	IPR001986	Enolpyruvate transferase domain	Domain
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M [auth W], N [auth X], O [auth Y], P [auth Z]	IPR005750	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Family
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M [auth W], N [auth X], O [auth Y], P [auth Z]	IPR013792	RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta	Homologous Superfamily
A, B, C, D, E, A, B, C, D, E, F, G, H, I, J, K, L, M [auth W], N [auth X], O [auth Y], P [auth Z]	IPR036968	Enolpyruvate transferase domain superfamily	Homologous Superfamily