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Crystal Structure of the Human GGA1 GAT domain External Resource: Annotation Domain Annotation: SCOP2 Classification SCOP2 Database Homepage Chains Type Family Name Domain Identifier Family Identifier Provenance Source (Version) A SCOP2B Superfamily GAT-like domain 8032224 3001306 SCOP2B (2022-06-29)
Chains Family Name Domain Identifier Architecture Possible Homology Homology Topology Family Provenance Source (Version) A PF03127 e1oxzA1 A: alpha bundles X: Spectrin repeat-like H: GAT-like domain (From Topology) T: GAT-like domain F: PF03127 ECOD (1.6)
Chains Accession Name Description Comments Source PF18308 N-terminal extension of GAT domain (GGA_N-GAT) N-terminal extension of GAT domain - Family PF03127 GAT domain (GAT) GAT domain The GAT domain is responsible for binding of GGA proteins to several members of the ARF family including ARF1 [1] and ARF3. The GAT domain stabilises membrane bound ARF1 in its GTP bound state, by interfering with GAP proteins [2]. Domain
Chains Polymer Molecular Function Biological Process Cellular Component ADP-ribosylation factor binding protein GGA1
Chains Drug Target   Associated Disease Pharos :  Q9UJY5