1OGO

Dex49A from Penicillium minioluteum complex with isomaltose

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Structure Motif: Primary M-CSA Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A [auth X]	d1ogox2	All beta proteins	Single-stranded right-handed beta-helix	Pectin lyase-like	Dextranase, catalytic domain	Dextranase, catalytic domain	(Talaromyces minioluteus ) [TaxId: 28574 ],	SCOPe (2.08)
A [auth X]	d1ogox1	All beta proteins	Dextranase, N-terminal domain	Dextranase, N-terminal domain	Dextranase, N-terminal domain	Dextranase, N-terminal domain	(Talaromyces minioluteus ) [TaxId: 28574 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth X]	SCOP2B Superfamily	Pectin lyase-like	8037481	3001746	SCOP2B (2022-06-29)
A [auth X]	SCOP2B Superfamily	Dextranase N-terminal domain	8037480	3001597	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth X]	Glyco_hydro_49N	e1ogoX1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Dextranase, N-terminal domain (From Topology)	T: Dextranase, N-terminal domain	F: Glyco_hydro_49N	ECOD (1.6)
A [auth X]	Glyco_hydro_49	e1ogoX2	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Pectin lyase-like (From Topology)	T: Pectin lyase-like	F: Glyco_hydro_49	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth X]	2.60.350.10	Mainly Beta	Sandwich	Dex49a from penicillium minioluteum complex, domain 1	Dextranase, N-terminal	CATH (4.3.0)
A [auth X]	2.160.20.10	Mainly Beta	3 Solenoid	Pectate Lyase C-like	Single-stranded right-handed beta-helix, Pectin lyase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth X]	PF03718	Glycosyl hydrolase family 49 (Glyco_hydro_49)	Glycosyl hydrolase family 49	-	Repeat
A [auth X]	PF18783	Isopullulanase beta-solenoid repeat (IPU_b_solenoid)	Isopullulanase beta-solenoid repeat	-	Repeat
A [auth X]	PF17433	Glycosyl hydrolase family 49 N-terminal Ig-like domain (Glyco_hydro_49N)	Glycosyl hydrolase family 49 N-terminal Ig-like domain	Family of dextranase (EC 3.2.1.11) and isopullulanase (EC 3.2.1.57). Dextranase hydrolyses alpha-1,6-glycosidic bonds in dextran polymers. This domain corresponds to the N-terminal Ig-like fold.	Domain
A [auth X]	PF18841	Beta solenoid repeat from Dextranase (B_solenoid_dext)	Beta solenoid repeat from Dextranase	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth X]	DEXTRANASE	dextranase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity	metabolic process	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth X]	IPR023226	Glycoside hydrolase, family 49, N-terminal domain	Domain
A [auth X]	IPR012334	Pectin lyase fold	Homologous Superfamily
A [auth X]	IPR041274	Isopullulanase beta-solenoid repeat	Repeat
A [auth X]	IPR005192	Glycoside hydrolase, family 49, C-terminal	Domain
A [auth X]	IPR041402	Dextranase, beta solenoid repeat	Repeat
A [auth X]	IPR035953	Dextranase, N-terminal	Homologous Superfamily
A [auth X]	IPR011050	Pectin lyase fold/virulence factor	Homologous Superfamily

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

Chains	Enzyme Name	Description	Catalytic Residues
A [auth X]	dextranase M-CSA #690	Dextranase catalyzes the hydrolysis of the alpha-1,6-glycosidic linkage in dextran polymers. The enzyme cleaves the linkages within the dextran molecule and releases shorter isomaltosaccharides. Belongs to the glycosyl hydrolase 49 family.	Defined by 2 residues: ASP:A-376 [auth X-376]ASP:A-395 [auth X-395] \| Explore in 3D: M-CSA Motif Definition Search M-CSA Motif EC: 3.2.1.11 (PDB Primary Data) Search M-CSA Motif + EC 3.2.1.11

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.