Annotations: 1O18

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
I [auth K]	d1o18k_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
L [auth N]	d1o18n_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
C [auth E]	d1o18e_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
F [auth H]	d1o18h_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
O [auth Q]	d1o18q_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
D [auth F]	d1o18f_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
G [auth I]	d1o18i_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
J [auth L]	d1o18l_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
M [auth O]	d1o18o_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
P [auth R]	d1o18r_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
Q [auth 1]	d1o181_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
R [auth 2]	d1o182_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
AA [auth W]	d1o18w_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
BA [auth X]	d1o18x_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
CA [auth Y]	d1o18y_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
DA [auth Z]	d1o18z_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
S [auth 3]	d1o183_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
T [auth 4]	d1o184_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
U [auth 5]	d1o185_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
V [auth 6]	d1o186_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
W [auth 7]	d1o187_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
X [auth 8]	d1o188_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
Y [auth 9]	d1o189_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
Z [auth V]	d1o18v_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
B [auth D]	d1o18d_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
N [auth P]	d1o18p_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
A	d1o18a_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
E [auth G]	d1o18g_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
H [auth J]	d1o18j_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)
K [auth M]	d1o18m_	Low resolution protein structures	Muscle protein complexes	Muscle protein complexes	Muscle protein complexes	Averaged rigor crossbridges from tomograms of insect flight muscle	(Gallus gallus ) [TaxId: 9031 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
I [auth K]	SCOP2B Superfamily	EF-hand	8062903	3001983	SCOP2B (2022-06-29)
L [auth N]	SCOP2B Superfamily	EF-hand	8062903	3001983	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	EF-hand	8062903	3001983	SCOP2B (2022-06-29)
F [auth H]	SCOP2B Superfamily	EF-hand	8062903	3001983	SCOP2B (2022-06-29)
O [auth Q]	SCOP2B Superfamily	EF-hand	8062903	3001983	SCOP2B (2022-06-29)
Q [auth 1]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
Q [auth 1]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
R [auth 2]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
R [auth 2]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
AA [auth W]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
AA [auth W]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
BA [auth X]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
BA [auth X]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
CA [auth Y]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
CA [auth Y]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
DA [auth Z]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
DA [auth Z]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
S [auth 3]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
S [auth 3]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
T [auth 4]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
T [auth 4]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
U [auth 5]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
U [auth 5]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
V [auth 6]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
V [auth 6]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
W [auth 7]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
W [auth 7]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
X [auth 8]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
X [auth 8]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
Y [auth 9]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)
Y [auth 9]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
Z [auth V]	SCOP2B Superfamily	Actin-like ATPases	8040506	3000092	SCOP2B (2022-06-29)
Z [auth V]	SCOP2B Superfamily	Actin-like ATPases	8040509	3000092	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
I [auth K]	F_UNCLASSIFIED	e1o18K2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
I [auth K]	PF13405	e1o18K1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13405	ECOD (1.6)
L [auth N]	F_UNCLASSIFIED	e1o18N2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
L [auth N]	PF13405	e1o18N1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13405	ECOD (1.6)
C [auth E]	F_UNCLASSIFIED	e1o18E2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
C [auth E]	PF13405	e1o18E1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13405	ECOD (1.6)
F [auth H]	F_UNCLASSIFIED	e1o18H2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
F [auth H]	PF13405	e1o18H1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13405	ECOD (1.6)
O [auth Q]	F_UNCLASSIFIED	e1o18Q2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
O [auth Q]	PF13405	e1o18Q1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13405	ECOD (1.6)
D [auth F]	F_UNCLASSIFIED	e1o18F2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
D [auth F]	PF13499	e1o18F4	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13499	ECOD (1.6)
G [auth I]	F_UNCLASSIFIED	e1o18I2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
G [auth I]	PF13499	e1o18I4	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13499	ECOD (1.6)
J [auth L]	F_UNCLASSIFIED	e1o18L2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
J [auth L]	PF13499	e1o18L4	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13499	ECOD (1.6)
M [auth O]	F_UNCLASSIFIED	e1o18O2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
M [auth O]	PF13499	e1o18O4	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13499	ECOD (1.6)
P [auth R]	F_UNCLASSIFIED	e1o18R2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
P [auth R]	PF13499	e1o18R4	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13499	ECOD (1.6)
Q [auth 1]	PF00022	e1o1813	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
R [auth 2]	PF00022	e1o1823	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
AA [auth W]	PF00022	e1o18W3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
BA [auth X]	PF00022	e1o18X3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
CA [auth Y]	PF00022	e1o18Y3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
DA [auth Z]	PF00022	e1o18Z3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
S [auth 3]	PF00022	e1o1833	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
T [auth 4]	PF00022	e1o1843	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
U [auth 5]	PF00022	e1o1853	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
V [auth 6]	PF00022	e1o1861	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
W [auth 7]	PF00022	e1o1873	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
X [auth 8]	PF00022	e1o1883	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
Y [auth 9]	PF00022	e1o1893	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
Z [auth V]	PF00022	e1o18V3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: PF00022	ECOD (1.6)
B [auth D]	PF02736	e1o18D1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF02736	ECOD (1.6)
B [auth D]	PF00612	e1o18D2	A: alpha bundles	X: Myosin VI lever arm (From Topology)	H: Myosin VI lever arm (From Topology)	T: Myosin VI lever arm	F: PF00612	ECOD (1.6)
B [auth D]	PF00063	e1o18D3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00063	ECOD (1.6)
N [auth P]	PF02736	e1o18P1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF02736	ECOD (1.6)
N [auth P]	PF00612	e1o18P2	A: alpha bundles	X: Myosin VI lever arm (From Topology)	H: Myosin VI lever arm (From Topology)	T: Myosin VI lever arm	F: PF00612	ECOD (1.6)
N [auth P]	PF00063	e1o18P3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00063	ECOD (1.6)
A	PF02736	e1o18A3	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF02736	ECOD (1.6)
A	PF00612	e1o18A1	A: alpha bundles	X: Myosin VI lever arm (From Topology)	H: Myosin VI lever arm (From Topology)	T: Myosin VI lever arm	F: PF00612	ECOD (1.6)
A	PF00063	e1o18A2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00063	ECOD (1.6)
E [auth G]	PF02736	e1o18G1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF02736	ECOD (1.6)
E [auth G]	PF00612	e1o18G3	A: alpha bundles	X: Myosin VI lever arm (From Topology)	H: Myosin VI lever arm (From Topology)	T: Myosin VI lever arm	F: PF00612	ECOD (1.6)
E [auth G]	PF00063	e1o18G2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00063	ECOD (1.6)
H [auth J]	PF02736	e1o18J2	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF02736	ECOD (1.6)
H [auth J]	PF00612	e1o18J1	A: alpha bundles	X: Myosin VI lever arm (From Topology)	H: Myosin VI lever arm (From Topology)	T: Myosin VI lever arm	F: PF00612	ECOD (1.6)
H [auth J]	PF00063	e1o18J3	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00063	ECOD (1.6)
K [auth M]	PF02736	e1o18M3	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF02736	ECOD (1.6)
K [auth M]	PF00612	e1o18M1	A: alpha bundles	X: Myosin VI lever arm (From Topology)	H: Myosin VI lever arm (From Topology)	T: Myosin VI lever arm	F: PF00612	ECOD (1.6)
K [auth M]	PF00063	e1o18M2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00063	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], R [auth 2], S [auth 3], T [auth 4], U [auth 5], V [auth 6], W [auth 7], X [auth 8], Y [auth 9], Z [auth V]	PF00022	Actin (Actin)	Actin	-	Family
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	PF02736	Myosin N-terminal SH3-like domain (Myosin_N)	Myosin N-terminal SH3-like domain	This domain has an SH3-like fold. It is found at the N-terminus of many but not all myosins. The function of this domain is unknown.	Domain
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	PF00063	Myosin head (motor domain) (Myosin_head)	Myosin head (motor domain)	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
C [auth E], F [auth H], I [auth K], L [auth N], O [auth Q]	SKELETAL MUSCLE MYOSIN II REGULATORY LIGHT CHAIN	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding	multicellular organismal process system process muscle contraction muscle system process developmental process muscle structure development skeletal muscle organ development skeletal muscle tissue development anatomical structure development animal organ development muscle tissue development muscle organ development tissue development	intracellular anatomical structure cytoplasm cellular anatomical entity intracellular organelle protein-containing complex cytoskeleton organelle intracellular non-membrane-bounded organelle actin cytoskeleton non-membrane-bounded organelle myosin complex
D [auth F], G [auth I], J [auth L], M [auth O], P [auth R]	SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding	-	protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle myosin II complex non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle myosin II complex non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber supramolecular polymer supramolecular complex
AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], R [auth 2], S [auth 3], T [auth 4], U [auth 5], V [auth 6], W [auth 7], X [auth 8], Y [auth 9], Z [auth V]	SKELETAL MUSCLE ACTIN	cytoskeletal protein binding titin binding protein binding binding cation binding ion binding calcium ion binding metal ion binding small molecule binding protein domain specific binding hydrolase activity catalytic activity troponin I binding cytoskeletal motor activator activity cytoskeletal protein binding titin binding protein binding binding cation binding ion binding calcium ion binding metal ion binding small molecule binding protein domain specific binding hydrolase activity catalytic activity troponin I binding cytoskeletal motor activator activity cytoskeletal motor regulator activity molecular function activator activity molecular function regulator activity magnesium ion binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding myosin heavy chain binding myosin binding tropomyosin binding calcium-dependent protein binding identical protein binding actin monomer binding actin binding	developmental process mesenchyme migration multicellular organismal process mesenchyme morphogenesis animal organ development mesenchyme development tissue development tissue morphogenesis anatomical structure morphogenesis tissue migration anatomical structure development animal organ morphogenesis myotube cell development skeletal muscle fiber development developmental process mesenchyme migration multicellular organismal process mesenchyme morphogenesis animal organ development mesenchyme development tissue development tissue morphogenesis anatomical structure morphogenesis tissue migration anatomical structure development animal organ morphogenesis myotube cell development skeletal muscle fiber development cellular developmental process skeletal muscle tissue development cell development muscle cell differentiation myotube differentiation muscle structure development skeletal muscle organ development muscle cell development cell differentiation cellular process muscle tissue development muscle organ development striated muscle cell differentiation regulation of cellular process cellular biosynthetic process positive regulation of biological process positive regulation of cellular metabolic process positive regulation of macromolecule biosynthetic process positive regulation of metabolic process organic substance metabolic process positive regulation of biosynthetic process organic substance biosynthetic process positive regulation of macromolecule metabolic process positive regulation of cellular process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation regulation of cellular metabolic process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process regulation of cellular biosynthetic process regulation of gene expression biosynthetic process positive regulation of gene expression regulation of macromolecule biosynthetic process metabolic process macromolecule metabolic process regulation of metabolic process positive regulation of cellular biosynthetic process cellular component assembly involved in morphogenesis non-membrane-bounded organelle assembly skeletal myofibril assembly cellular component organization cellular component biogenesis striated muscle cell development cellular anatomical entity morphogenesis cellular component assembly actin filament-based process cellular component organization or biogenesis skeletal muscle thin filament assembly actin cytoskeleton organization actomyosin structure organization organelle assembly actin filament organization organelle organization myofibril assembly anatomical structure formation involved in morphogenesis supramolecular fiber organization cytoskeleton organization protein polymerization actin polymerization or depolymerization actin filament polymerization protein-containing complex organization protein-containing complex assembly actin filament bundle organization actin filament bundle assembly	intracellular anatomical structure skeletal muscle myofibril cellular anatomical entity intracellular organelle organelle intracellular non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber myofibril supramolecular polymer supramolecular complex non-membrane-bounded organelle cell projection intracellular anatomical structure skeletal muscle myofibril cellular anatomical entity intracellular organelle organelle intracellular non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber myofibril supramolecular polymer supramolecular complex non-membrane-bounded organelle cell projection cell leading edge plasma membrane bounded cell projection lamellipodium cytoskeleton actin filament bundle actin cytoskeleton actomyosin stress fiber contractile actin filament bundle polymeric cytoskeletal fiber actin filament protein-containing complex filamentous actin cell body striated muscle thin filament myofilament sarcomere actin-based cell projection filopodium
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	SKELETAL MUSCLE MYOSIN II	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding cytoskeletal protein binding actin binding protein-containing complex binding protein binding actin filament binding calmodulin binding cytoskeletal motor activity microfilament motor activity ATP-dependent activity	multicellular organismal process system process muscle contraction muscle system process	protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle myosin II complex non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle myosin II complex non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber myofibril supramolecular polymer supramolecular complex myosin filament

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C [auth E], F [auth H], I [auth K], L [auth N], O [auth Q]	IPR018247	EF-Hand 1, calcium-binding site	Binding Site
C [auth E], F [auth H], I [auth K], L [auth N], O [auth Q]	IPR002048	EF-hand domain	Domain
C [auth E], F [auth H], I [auth K], L [auth N], O [auth Q]	IPR011992	EF-hand domain pair	Homologous Superfamily
D [auth F], G [auth I], J [auth L], M [auth O], P [auth R]	IPR002048	EF-hand domain	Domain
D [auth F], G [auth I], J [auth L], M [auth O], P [auth R]	IPR011992	EF-hand domain pair	Homologous Superfamily
AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], R [auth 2], S [auth 3], T [auth 4], U [auth 5], V [auth 6], W [auth 7], X [auth 8], Y [auth 9], Z [auth V]	IPR020902	Actin/actin-like conserved site	Conserved Site
AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], R [auth 2], S [auth 3], T [auth 4], U [auth 5], V [auth 6], W [auth 7], X [auth 8], Y [auth 9], Z [auth V]	IPR043129	ATPase, nucleotide binding domain	Homologous Superfamily
AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], R [auth 2], S [auth 3], T [auth 4], U [auth 5], V [auth 6], W [auth 7], X [auth 8], Y [auth 9], Z [auth V]	IPR004001	Actin, conserved site	Conserved Site
AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], AA [auth W], BA [auth X], CA [auth Y], DA [auth Z], Q [auth 1], R [auth 2], S [auth 3], T [auth 4], U [auth 5], V [auth 6], W [auth 7], X [auth 8], Y [auth 9], Z [auth V]	IPR004000	Actin family	Family
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	IPR036961	Kinesin motor domain superfamily	Homologous Superfamily
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	IPR014751	DNA repair protein XRCC4-like, C-terminal	Homologous Superfamily
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	IPR001609	Myosin head, motor domain	Domain
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	IPR002928	Myosin tail	Domain
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	IPR004009	Myosin, N-terminal, SH3-like	Domain
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	IPR008989	Myosin S1 fragment, N-terminal	Homologous Superfamily
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	IPR000048	IQ motif, EF-hand binding site	Binding Site
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B [auth D], E [auth G], H [auth J], K [auth M], A, B [auth D], E [auth G], H [auth J], K [auth M], N [auth P]	MLY	Parent Component: LYS RESID: AA0075 PSI-MOD : N6,N6-dimethyl-L-lysine MOD:00084