1NRZ

Crystal structure of the IIBSor domain of the sorbose permease from Klebsiella pneumoniae solved to 1.75A resolution

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1nrza_	Alpha and beta proteins (a/b)	PTS IIb component	PTS IIb component	PTS IIb component	Sorbose permease subunit IIb , EIIb-sor	(Klebsiella pneumoniae ) [TaxId: 573 ],	SCOPe (2.08)
B	d1nrzb_	Alpha and beta proteins (a/b)	PTS IIb component	PTS IIb component	PTS IIb component	Sorbose permease subunit IIb , EIIb-sor	(Klebsiella pneumoniae ) [TaxId: 573 ],	SCOPe (2.08)
C	d1nrzc_	Alpha and beta proteins (a/b)	PTS IIb component	PTS IIb component	PTS IIb component	Sorbose permease subunit IIb , EIIb-sor	(Klebsiella pneumoniae ) [TaxId: 573 ],	SCOPe (2.08)
D	d1nrzd_	Alpha and beta proteins (a/b)	PTS IIb component	PTS IIb component	PTS IIb component	Sorbose permease subunit IIb , EIIb-sor	(Klebsiella pneumoniae ) [TaxId: 573 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	PTS IIb component-like	8021194	4000403	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	PTS IIb component	8033574	3000207	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	PTS IIb component	8033574	3000207	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	PTS IIb component	8033574	3000207	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	PTS IIb component	8033574	3000207	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03830	e1nrzA1	A: a/b three-layered sandwiches	X: PTS IIb component (From Topology)	H: PTS IIb component (From Topology)	T: PTS IIb component	F: PF03830	ECOD (1.6)
B	PF03830	e1nrzB1	A: a/b three-layered sandwiches	X: PTS IIb component (From Topology)	H: PTS IIb component (From Topology)	T: PTS IIb component	F: PF03830	ECOD (1.6)
C	PF03830	e1nrzC1	A: a/b three-layered sandwiches	X: PTS IIb component (From Topology)	H: PTS IIb component (From Topology)	T: PTS IIb component	F: PF03830	ECOD (1.6)
D	PF03830	e1nrzD1	A: a/b three-layered sandwiches	X: PTS IIb component (From Topology)	H: PTS IIb component (From Topology)	T: PTS IIb component	F: PF03830	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.35.10	Alpha Beta	3-Layer(aba) Sandwich	Fructose Permease	Phosphotransferase system, sorbose subfamily IIB component	CATH (4.3.0)
B	3.40.35.10	Alpha Beta	3-Layer(aba) Sandwich	Fructose Permease	Phosphotransferase system, sorbose subfamily IIB component	CATH (4.3.0)
C	3.40.35.10	Alpha Beta	3-Layer(aba) Sandwich	Fructose Permease	Phosphotransferase system, sorbose subfamily IIB component	CATH (4.3.0)
D	3.40.35.10	Alpha Beta	3-Layer(aba) Sandwich	Fructose Permease	Phosphotransferase system, sorbose subfamily IIB component	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF03830	PTS system sorbose subfamily IIB component (PTSIIB_sorb)	PTS system sorbose subfamily IIB component	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	PTS system, sorbose-specific IIB component	kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups monosaccharide transmembrane transporter activity sugar transmembrane transporter activity sorbose transmembrane transporter activity protein-N(PI)-phosphohistidine-sugar phosphotransferase activity hexose transmembrane transporter activity phosphotransferase activity, alcohol group as acceptor glucose transmembrane transporter activity active transmembrane transporter activity protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity transporter activity kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups monosaccharide transmembrane transporter activity sugar transmembrane transporter activity sorbose transmembrane transporter activity protein-N(PI)-phosphohistidine-sugar phosphotransferase activity hexose transmembrane transporter activity phosphotransferase activity, alcohol group as acceptor glucose transmembrane transporter activity active transmembrane transporter activity protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity D-glucose transmembrane transporter activity	phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system transport organic substance transport import across plasma membrane carbohydrate import across plasma membrane carbohydrate transport establishment of localization phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system transport organic substance transport import across plasma membrane carbohydrate import across plasma membrane carbohydrate transport establishment of localization transmembrane transport localization carbohydrate transmembrane transport	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR036667	Phosphotransferase system, sorbose subfamily IIB component superfamily	Homologous Superfamily
A, B, C, D	IPR018455	Phosphotransferase system, sorbose subfamily IIB component, subgroup	Family
A, B, C, D	IPR004720	Phosphotransferase system, sorbose subfamily IIB component	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.