1MW7

X-RAY STRUCTURE OF Y162_HELPY NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PR6

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1mw7a_	Multi-domain proteins (alpha and beta)	YebC-like	YebC-like	YebC-like	Hypothetical protein HP0162	(Helicobacter pylori ) [TaxId: 210 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	TACO1-like	8031463	4002873	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Homeodomain-like	8054408	3000001	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	TACO1 C-terminal domain-like	8043841	3001835	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF20772	e1mw7A1	A: alpha arrays	X: Helical bundle domain in YebC-like proteins (From Topology)	H: Helical bundle domain in YebC-like proteins (From Topology)	T: Helical bundle domain in YebC-like proteins	F: PF20772	ECOD (1.6)
A	F_UNCLASSIFIED	e1mw7A2	A: a+b two layers	X: Alpha-beta plaits	H: Ferredoxin-like domain in YebC (From Topology)	T: Ferredoxin-like domain in YebC	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF01709	e1mw7A3	A: a+b two layers	X: a+b domain in YebC-like proteins (From Topology)	H: a+b domain in YebC-like proteins (From Topology)	T: a+b domain in YebC-like proteins	F: PF01709	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.10.200	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Integrase, N-terminal zinc-binding domain	CATH (4.3.0)
A	3.30.70.980	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	YebC, transcriptional regulation domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF20772	TACO1/YebC protein N-terminal domain (TACO1_YebC_N)	TACO1/YebC protein N-terminal domain	This entry represents the N-terminal helical bundle domain from proteins in the TACO1/YebC family which are thought to act as transcriptional regulators. In mammals, The TACO1 protein activates the translation of mitochondrially-encoded COX1 [2,4]. I ...	This entry represents the N-terminal helical bundle domain from proteins in the TACO1/YebC family which are thought to act as transcriptional regulators. In mammals, The TACO1 protein activates the translation of mitochondrially-encoded COX1 [2,4]. In bacteria, it negatively regulates the quorum-sensing response regulator by binding to its promoter region [3].	Domain
A	PF01709	TACO1/YebC second and third domain (Transcrip_reg)	TACO1/YebC second and third domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	HYPOTHETICAL PROTEIN HP0162	DNA binding binding organic cyclic compound binding nucleic acid binding	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process cellular process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR017856	Integrase-like, N-terminal	Homologous Superfamily
A	IPR048300	TACO1/YebC-like, second and third domains	Domain
A	IPR049083	TACO1/YebC-like, N-terminal domain	Domain
A	IPR002876	Transcriptional regulator TACO1-like	Family
A	IPR029072	YebC-like	Homologous Superfamily
A	IPR026564	Transcriptional regulator TACO1-like, domain 3	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.